Hairgrow
Generic Name
Minoxidil Topical Solution
Manufacturer
Square Pharmaceuticals Ltd.
Country
Bangladesh
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Description
Overview of the medicine
Hairgrow (Minoxidil) is a topical solution used to treat androgenetic alopecia (male and female pattern baldness) by stimulating hair regrowth. It is applied directly to the scalp.
Uses & Indications
Dosage
Adults
Apply 1 mL of 5% solution to the affected area of the scalp twice daily.
Elderly
No specific dosage adjustment required for elderly patients. Use as adult dosage.
Renal_impairment
No dosage adjustment required for topical use.
How to Take
Ensure scalp is dry. Apply 1 mL solution to the affected area using the applicator, gently rub it in. Wash hands thoroughly after application. Do not apply to other body parts. Avoid contact with eyes, nose, and mouth.
Mechanism of Action
Minoxidil is believed to stimulate hair growth by widening blood vessels and increasing blood flow to the hair follicles, thereby prolonging the anagen (growth) phase of hair follicles and increasing their size. It may also directly stimulate hair follicle cells.
Pharmacokinetics
Onset
Hair regrowth typically begins after 2-4 months of consistent use.
Excretion
Mainly excreted by the kidneys, primarily as glucuronide conjugates.
Half life
Systemic half-life is approximately 4.2 hours.
Absorption
Approximately 1.4-1.7% of topically applied Minoxidil is absorbed systemically. Absorption is increased with damaged skin.
Metabolism
Absorbed Minoxidil is primarily metabolized by hepatic glucuronidation.
Side Effects
Contraindications
- Hypersensitivity to Minoxidil or any component of the formulation.
- Patients with pheochromocytoma (for oral Minoxidil, though topical absorption is minimal).
- Existing heart disease, especially hypertension or angina (use with caution).
- Not for sudden, patchy, or unexplained hair loss.
Drug Interactions
Guanethidine
May cause orthostatic hypotension if used concurrently with oral Minoxidil. Not significant for topical.
Topical corticosteroids/retinoids
May enhance Minoxidil absorption.
Storage
Store at room temperature (15-30°C), away from direct sunlight and heat. Keep out of reach of children.
Overdose
Accidental ingestion or excessive topical application may lead to systemic effects such as hypotension, tachycardia, fluid retention, and dizziness. Treatment is symptomatic and supportive.
Pregnancy & Lactation
Not recommended during pregnancy or breastfeeding due to potential systemic absorption and unknown effects on the fetus/infant. Consult a doctor.
Side Effects
Contraindications
- Hypersensitivity to Minoxidil or any component of the formulation.
- Patients with pheochromocytoma (for oral Minoxidil, though topical absorption is minimal).
- Existing heart disease, especially hypertension or angina (use with caution).
- Not for sudden, patchy, or unexplained hair loss.
Drug Interactions
Guanethidine
May cause orthostatic hypotension if used concurrently with oral Minoxidil. Not significant for topical.
Topical corticosteroids/retinoids
May enhance Minoxidil absorption.
Storage
Store at room temperature (15-30°C), away from direct sunlight and heat. Keep out of reach of children.
Overdose
Accidental ingestion or excessive topical application may lead to systemic effects such as hypotension, tachycardia, fluid retention, and dizziness. Treatment is symptomatic and supportive.
Pregnancy & Lactation
Not recommended during pregnancy or breastfeeding due to potential systemic absorption and unknown effects on the fetus/infant. Consult a doctor.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
Typically 2-3 years from the date of manufacture, check product label.
Availability
Pharmacies, Online stores
Approval Status
FDA Approved
Patent Status
Off-patent
Clinical Trials
Extensive clinical trials have demonstrated Minoxidil's efficacy in stimulating hair growth for androgenetic alopecia in both men and women. Studies show increased hair count and density compared to placebo.
Lab Monitoring
- No specific routine lab monitoring is required for topical Minoxidil use.
Doctor Notes
- Emphasize patient education on consistent application for optimal results.
- Counsel patients on potential initial shedding (telogen effluvium) which is temporary.
- Advise patients to report any severe scalp irritation or systemic side effects immediately.
Patient Guidelines
- Use consistently twice daily for at least 4 months for visible results.
- Wash hands thoroughly after applying the solution.
- Do not use on irritated, inflamed, infected, or painful scalp.
- Avoid contact with eyes and other mucous membranes.
- Do not use if you have heart disease without consulting a doctor.
Missed Dose Advice
If you miss a dose, apply it as soon as you remember. If it is almost time for your next dose, skip the missed dose and resume your regular dosing schedule. Do not apply a double dose.
Driving Precautions
Generally, Hairgrow (Minoxidil) has no known effect on the ability to drive or operate machinery. However, if you experience dizziness, avoid such activities.
Lifestyle Advice
- Maintain a balanced diet rich in vitamins and minerals.
- Manage stress, as it can contribute to hair loss.
- Avoid harsh hair treatments and excessive heat styling.
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Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.
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