Kuit
Generic Name
Alprazolam
Manufacturer
Unspecified Manufacturer
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| kuit 05 mg tablet | ৳ 5.75 | ৳ 57.50 |
Description
Overview of the medicine
Kuit 0.5 mg Tablet contains Alprazolam, a benzodiazepine primarily used for the management of anxiety disorders and panic disorder.
Uses & Indications
Dosage
Adults
Initial dose: 0.25-0.5 mg three times daily. Max: 4 mg daily in divided doses.
Elderly
Initial dose: 0.25 mg two to three times daily. Gradually increase if needed and tolerated.
Renal_impairment
No specific dose adjustment recommendations, but caution is advised. Start with lower doses.
How to Take
Take orally with or without food. Do not crush or chew if it's an extended-release form (though Kuit is likely immediate-release).
Mechanism of Action
Alprazolam acts by enhancing the activity of gamma-aminobutyric acid (GABA), a natural chemical in the brain, which leads to a calming effect on the central nervous system.
Pharmacokinetics
Onset
15-30 minutes.
Excretion
Mainly excreted in the urine as metabolites.
Half life
Approximately 11-12 hours.
Absorption
Rapidly absorbed from the gastrointestinal tract.
Metabolism
Extensively metabolized in the liver, primarily by CYP3A4.
Side Effects
Contraindications
- •Known hypersensitivity to alprazolam or other benzodiazepines.
- •Acute narrow-angle glaucoma.
Drug Interactions
Digoxin
May increase digoxin levels.
Opioids
Increased risk of sedation, respiratory depression, coma, and death.
Alcohol and other CNS depressants
Additive CNS depressant effects.
CYP3A4 Inhibitors (e.g., Ketoconazole, Itraconazole)
Increased alprazolam levels, leading to enhanced effects.
Storage
Store below 30°C in a dry place, away from light and moisture. Keep out of reach of children.
Overdose
Symptoms include somnolence, confusion, impaired coordination, diminished reflexes, and coma. Management is primarily supportive, including airway management and intravenous fluids. Flumazenil may be used in severe cases but carries risks.
Pregnancy & Lactation
Pregnancy Category D: May cause fetal harm. Not recommended during pregnancy, especially in the first trimester. Breastfeeding: Alprazolam passes into breast milk and is not recommended during lactation due to potential sedative effects on the infant.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
Typically 2-3 years from manufacturing date.
Availability
Available in pharmacies and hospitals
Approval Status
Approved by regulatory authorities worldwide
Patent Status
Off-patent
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Global Brand Names
International brand names for this medicine
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