Metrion
Generic Name
Metrion
Manufacturer
PharmaGen Ltd. (Fictional)
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| metrion 400 mg tablet | ৳ 2.01 | ৳ 20.06 |
| metrion 500 mg injection | ৳ 80.24 | N/A |
Description
Overview of the medicine
Metrion is a hypothetical broad-spectrum antibiotic indicated for various bacterial infections. It works by inhibiting bacterial cell wall synthesis. (Fictional)
Uses & Indications
Dosage
Adults
500 mg orally every 12 hours for 7-14 days.
Elderly
No specific dose adjustment required unless significant renal impairment is present.
Renal_impairment
Dose adjustment required; e.g., 250 mg every 12-24 hours for CrCl < 30 mL/min.
How to Take
Can be taken with or without food. To minimize gastrointestinal upset, it is recommended to take with food. Complete the full course of treatment.
Mechanism of Action
Metrion selectively binds to penicillin-binding proteins (PBPs) located in the bacterial cell wall, thereby inhibiting the synthesis of the peptidoglycan layer. This leads to cell lysis and bacterial death. (Fictional)
Pharmacokinetics
Onset
Within 1-2 hours.
Excretion
Mainly renal excretion, with a small portion via bile.
Half life
Approximately 4-6 hours.
Absorption
Rapidly absorbed after oral administration, bioavailability approximately 80-90%.
Metabolism
Primarily hepatic metabolism, with some active metabolites.
Side Effects
Contraindications
- Hypersensitivity to Metrion or other cephalosporins
- History of severe penicillin allergy
Drug Interactions
Probenecid
Increases Metrion plasma levels by inhibiting renal tubular secretion.
Anticoagulants (e.g., Warfarin)
May enhance anticoagulant effect; monitor INR.
Storage
Store below 30°C in a dry place, away from direct sunlight and moisture. Keep out of reach of children.
Overdose
Symptoms of overdose may include nausea, vomiting, diarrhea, and convulsions. Management is symptomatic and supportive; hemodialysis may be considered in severe cases. (Fictional)
Pregnancy & Lactation
Pregnancy Category B. Use only if clearly needed. Excreted in breast milk in small amounts; use with caution.
Side Effects
Contraindications
- Hypersensitivity to Metrion or other cephalosporins
- History of severe penicillin allergy
Drug Interactions
Probenecid
Increases Metrion plasma levels by inhibiting renal tubular secretion.
Anticoagulants (e.g., Warfarin)
May enhance anticoagulant effect; monitor INR.
Storage
Store below 30°C in a dry place, away from direct sunlight and moisture. Keep out of reach of children.
Overdose
Symptoms of overdose may include nausea, vomiting, diarrhea, and convulsions. Management is symptomatic and supportive; hemodialysis may be considered in severe cases. (Fictional)
Pregnancy & Lactation
Pregnancy Category B. Use only if clearly needed. Excreted in breast milk in small amounts; use with caution.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
24 months from manufacturing date
Availability
Available in all pharmacies
Approval Status
Approved by DGDA (Hypothetical)
Patent Status
Patent pending (Hypothetical)
Clinical Trials
Phase III clinical trials demonstrated efficacy and safety in various bacterial infections. (Fictional)
Lab Monitoring
- Renal function tests (e.g., creatinine, BUN) in patients with pre-existing renal impairment
- Liver function tests (e.g., ALT, AST) if long-term treatment
- Complete blood count (CBC)
Doctor Notes
- Emphasize adherence to the full treatment course.
- Monitor for signs of allergic reactions, especially in patients with a history of drug allergies.
- Consider renal dose adjustment for impaired kidney function.
Patient Guidelines
- Take the medicine as prescribed, even if symptoms improve.
- Do not share this medication with others.
- Contact your doctor if symptoms worsen or new symptoms appear.
Missed Dose Advice
Take the missed dose as soon as you remember, unless it is almost time for your next dose. Do not double the dose.
Driving Precautions
May cause dizziness in some individuals. Exercise caution when driving or operating machinery until you know how Metrion affects you.
Lifestyle Advice
- Maintain good hydration by drinking plenty of fluids.
- Ensure adequate rest to support recovery.
- Avoid unnecessary use of antibiotics in the future.
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Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.
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