Micogyl
Generic Name
Metronidazole
Manufacturer
Square Pharmaceuticals Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| micogyl 500 mg injection | ৳ 80.00 | N/A |
Description
Overview of the medicine
Metronidazole is an antibiotic used to treat various bacterial and parasitic infections. It's effective against anaerobic bacteria and certain protozoa.
Uses & Indications
Dosage
Adults
Varies by infection. For severe anaerobic infections, 500 mg IV every 8 hours.
Elderly
Dosage adjustment may be required in elderly with impaired hepatic function.
Renal_impairment
No routine dosage adjustment for mild to moderate impairment; reduced dose for severe renal failure/dialysis.
How to Take
Administered by slow intravenous infusion over 30-60 minutes.
Mechanism of Action
Metronidazole is a nitroimidazole that works by damaging the DNA of anaerobic bacteria and protozoa, inhibiting nucleic acid synthesis.
Pharmacokinetics
Onset
Varies by indication, generally rapid for IV.
Excretion
Primarily renal (urine), some through feces.
Half life
Approximately 8 hours.
Absorption
Rapid and complete absorption after oral administration; IV administration bypasses absorption.
Metabolism
Primarily hepatic (liver) by oxidation.
Side Effects
Contraindications
- •Hypersensitivity to metronidazole or other nitroimidazole derivatives.
- •First trimester of pregnancy (relative).
Drug Interactions
Alcohol
Disulfiram-like reaction (nausea, vomiting, flushing).
Lithium
Increased lithium levels.
Warfarin
Enhanced anticoagulant effect.
Cimetidine
May prolong metronidazole half-life.
Phenobarbital
May decrease metronidazole half-life.
Storage
Store below 30°C, protect from light. Do not freeze.
Overdose
Symptomatic and supportive treatment. No specific antidote.
Pregnancy & Lactation
Use with caution during pregnancy, especially in the first trimester. Excreted into breast milk, consult doctor.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
Typically 2-3 years, varies by manufacturer.
Availability
Pharmacies, Hospitals
Approval Status
Approved
Patent Status
Generic
WHO Essential Medicine
YesAlternative Medicines in Bangladesh
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Global Brand Names
International brand names for this medicine
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