Mirogab
Generic Name
Mirogabalin
Manufacturer
Hypothetical Pharma
Country
Country of origin
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| mirogab 15 mg tablet | ৳ 45.00 | ৳ 450.00 |
Description
Overview of the medicine
Mirogabalin 15 mg tablet is used for the treatment of various types of neuropathic pain, such as diabetic peripheral neuropathic pain and postherpetic neuralgia.
Uses & Indications
Dosage
Adults
Initial dose is usually 5 mg twice daily or 10 mg once daily, titrated up to 15 mg twice daily based on individual response and tolerability.
Elderly
Dose adjustment may be required based on renal function. Initiate with lower doses.
Renal_impairment
Dosage should be adjusted based on creatinine clearance. Lower doses and/or less frequent administration may be necessary.
How to Take
Take orally with or without food. Swallow the tablet whole with water.
Mechanism of Action
Mirogabalin selectively binds to the α2δ-1 subunit of voltage-gated calcium channels (VGCCs) in the central nervous system, which is believed to reduce the release of excitatory neurotransmitters and alleviate neuropathic pain.
Pharmacokinetics
Onset
Typically within 1 to 2 hours.
Excretion
Primarily excreted unchanged in the urine via the kidneys.
Half life
Approximately 2 to 3 hours.
Absorption
Rapidly absorbed after oral administration, with peak plasma concentrations reached within 0.5 to 1.5 hours.
Metabolism
Minimally metabolized in the liver; largely excreted unchanged.
Side Effects
Contraindications
- •Hypersensitivity to mirogabalin or any component of the formulation.
Drug Interactions
Opioids
Potential for additive effects on CNS depression.
CNS Depressants
May enhance the central nervous system depressant effects (e.g., drowsiness, dizziness) when co-administered with alcohol, benzodiazepines, or other sedatives.
Storage
Store below 30°C, protected from light and moisture. Keep out of reach of children.
Overdose
Symptoms of overdose may include increased drowsiness, dizziness, and gastrointestinal disturbances. Management is supportive and symptomatic.
Pregnancy & Lactation
Mirogabalin is generally not recommended during pregnancy and lactation due to insufficient data and potential risks. Use only if the potential benefit justifies the potential risk to the fetus or infant.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
24 to 36 months from the manufacturing date.
Availability
Pharmacies and hospitals
Approval Status
Approved in some countries (e.g., Japan, South Korea)
Patent Status
Patent protected
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Global Brand Names
International brand names for this medicine
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