Moxigen
Generic Name
Moxifloxacin
Manufacturer
Square Pharmaceuticals Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| moxigen 05 eye ointment | ৳ 130.00 | N/A |
Description
Overview of the medicine
Moxigen 0.5% Eye Ointment is an ophthalmic antibiotic containing Moxifloxacin, a fourth-generation fluoroquinolone, used to treat bacterial conjunctivitis and other superficial ocular bacterial infections.
Uses & Indications
Dosage
Adults
Apply a small amount (approximately 1.5 cm strip) into the conjunctival sac three times a day for 7 days.
Elderly
No dosage adjustment is necessary for elderly patients.
Renal_impairment
No dosage adjustment is necessary for patients with renal impairment.
How to Take
For ophthalmic use only. Tilt head back, pull down the lower eyelid to form a pouch, apply a small ribbon of ointment into the pouch. Close eye gently. Avoid touching the tip of the tube to the eye or any other surface.
Mechanism of Action
Moxifloxacin inhibits bacterial DNA gyrase and topoisomerase IV, essential enzymes for bacterial DNA replication, transcription, repair, and recombination, leading to bacterial cell death.
Pharmacokinetics
Onset
Rapid onset of action, typically within hours for symptom relief.
Excretion
Excreted mainly in feces and urine as unchanged drug.
Half life
Systemic half-life is approximately 11-15 hours, but ocular exposure is localized.
Absorption
Minimal systemic absorption following ocular administration.
Metabolism
Minimally metabolized; primarily eliminated unchanged.
Side Effects
Contraindications
- Hypersensitivity to moxifloxacin, other quinolones, or any component of the ointment.
Drug Interactions
None significant for topical ophthalmic use
Due to minimal systemic absorption, no significant drug interactions are expected.
Storage
Store at room temperature (below 30°C/86°F). Do not freeze. Keep away from excessive heat and moisture. Keep out of reach of children.
Overdose
Overdose is unlikely with topical ophthalmic administration. If accidental ingestion occurs, seek medical advice. Topical overdose can be rinsed with lukewarm water.
Pregnancy & Lactation
Use during pregnancy only if the potential benefit justifies the potential risk to the fetus. Caution should be exercised when administered to a nursing mother due to unknown systemic excretion in breast milk.
Side Effects
Contraindications
- Hypersensitivity to moxifloxacin, other quinolones, or any component of the ointment.
Drug Interactions
None significant for topical ophthalmic use
Due to minimal systemic absorption, no significant drug interactions are expected.
Storage
Store at room temperature (below 30°C/86°F). Do not freeze. Keep away from excessive heat and moisture. Keep out of reach of children.
Overdose
Overdose is unlikely with topical ophthalmic administration. If accidental ingestion occurs, seek medical advice. Topical overdose can be rinsed with lukewarm water.
Pregnancy & Lactation
Use during pregnancy only if the potential benefit justifies the potential risk to the fetus. Caution should be exercised when administered to a nursing mother due to unknown systemic excretion in breast milk.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
Typically 24-36 months unopened. Discard 28 days after opening the tube, or as advised by pharmacist.
Availability
Pharmacies, Hospitals
Approval Status
Approved
Patent Status
Generic available
Clinical Trials
Extensive clinical trials have demonstrated the efficacy and safety of Moxifloxacin ophthalmic preparations for bacterial conjunctivitis and other superficial ocular infections.
Lab Monitoring
- No specific lab monitoring required for topical ophthalmic use.
Doctor Notes
- Ensure patient compliance for the full course of treatment to prevent recurrence and resistance.
- Advise patients about potential temporary blurred vision or mild irritation.
- Review alternative treatments if no significant improvement is observed within a few days of initiation.
Patient Guidelines
- Wash hands before and after application.
- Do not wear contact lenses during treatment.
- Avoid contaminating the tip of the tube.
- If using other eye medications, wait at least 5 minutes between applications.
Missed Dose Advice
Apply the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not apply a double dose to make up for a missed one.
Driving Precautions
May cause temporary blurred vision; if so, avoid driving or operating machinery until vision clears.
Lifestyle Advice
- Maintain good eye hygiene.
- Avoid rubbing eyes.
- Follow doctor's instructions strictly.
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Global Brand Names
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