Moxquin
Generic Name
Moxifloxacin Ophthalmic Solution 0.5%
Manufacturer
General Pharmaceuticals Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| moxquin 05 eye drop | ৳ 160.00 | N/A |
Description
Overview of the medicine
Moxquin 0.5% Eye Drop contains Moxifloxacin, a fluoroquinolone antibiotic, used to treat bacterial infections of the eye, such as bacterial conjunctivitis.
Uses & Indications
Dosage
Adults
Instill one drop in the affected eye(s) 3 times daily for 7 days. Do not exceed the prescribed duration.
Elderly
No specific dosage adjustment is required for elderly patients.
Renal_impairment
No specific dosage adjustment is required for patients with renal impairment.
How to Take
For ophthalmic use only. Tilt head back, pull down the lower eyelid to form a pouch, and instill the prescribed number of drops. Close eyes gently for a few seconds. Avoid touching the dropper tip to the eye or any other surface to prevent contamination.
Mechanism of Action
Moxifloxacin inhibits bacterial DNA gyrase and topoisomerase IV, enzymes essential for bacterial DNA replication, transcription, repair, and recombination. This leads to the disruption of bacterial DNA and cell death.
Pharmacokinetics
Onset
Onset of action is relatively rapid, with antimicrobial effects observed shortly after administration.
Excretion
Systemic moxifloxacin is excreted primarily via feces and urine. With ophthalmic use, systemic excretion is negligible.
Half life
Systemic half-life is approximately 11-15 hours, but local ophthalmic concentrations are much higher and sustained at the site of infection.
Absorption
Following topical ophthalmic administration, moxifloxacin is minimally absorbed into the systemic circulation. Plasma concentrations are generally below the limit of quantification.
Metabolism
Systemic moxifloxacin is primarily metabolized in the liver. However, due to minimal systemic absorption from ophthalmic administration, hepatic metabolism is negligible for topical use.
Side Effects
Contraindications
- Hypersensitivity to moxifloxacin, other quinolones, or any component of the formulation.
Drug Interactions
Systemic absorption
Due to minimal systemic absorption, clinically significant drug-drug interactions are unlikely with ophthalmic moxifloxacin.
Storage
Store at room temperature (15°C-25°C). Protect from light. Do not freeze. Keep out of reach of children.
Overdose
An overdose of ophthalmic moxifloxacin is unlikely. If accidentally ingested, seek medical advice or contact a poison control center.
Pregnancy & Lactation
Use during pregnancy or lactation only if the potential benefit justifies the potential risk to the fetus or infant. Consult a healthcare professional before use.
Side Effects
Contraindications
- Hypersensitivity to moxifloxacin, other quinolones, or any component of the formulation.
Drug Interactions
Systemic absorption
Due to minimal systemic absorption, clinically significant drug-drug interactions are unlikely with ophthalmic moxifloxacin.
Storage
Store at room temperature (15°C-25°C). Protect from light. Do not freeze. Keep out of reach of children.
Overdose
An overdose of ophthalmic moxifloxacin is unlikely. If accidentally ingested, seek medical advice or contact a poison control center.
Pregnancy & Lactation
Use during pregnancy or lactation only if the potential benefit justifies the potential risk to the fetus or infant. Consult a healthcare professional before use.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
Typically 2-3 years unopened. Discard 28 days after opening.
Availability
Pharmacies, Hospitals
Approval Status
Approved by relevant authorities (e.g., FDA, DGDA)
Patent Status
Patent expired, generic versions available
Clinical Trials
Moxifloxacin ophthalmic solution has undergone extensive clinical trials demonstrating its efficacy and safety for the treatment of bacterial conjunctivitis.
Lab Monitoring
- No specific laboratory monitoring is generally required for ophthalmic moxifloxacin.
Doctor Notes
- Remind patients about the importance of completing the full course of treatment to prevent antibiotic resistance.
- Educate patients on proper eye drop instillation technique to maximize efficacy and minimize contamination.
- Advise patients not to share eye drops with others.
Patient Guidelines
- Do not wear contact lenses if you have signs and symptoms of bacterial conjunctivitis.
- Use the medication for the full prescribed duration, even if symptoms improve.
- Avoid touching the dropper tip to any surface to prevent contamination.
- If you use other eye medications, wait at least 5 minutes between applications.
Missed Dose Advice
If a dose is missed, apply it as soon as you remember. If it is almost time for the next dose, skip the missed dose and continue with your regular dosing schedule. Do not apply a double dose to make up for a missed one.
Driving Precautions
Moxquin 0.5% Eye Drop may cause temporary blurring of vision immediately after instillation. Avoid driving or operating machinery until your vision clears.
Lifestyle Advice
- Maintain good ocular hygiene.
- Avoid rubbing your eyes.
- Wash hands thoroughly before and after applying eye drops.
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