Nesotem
Generic Name
Desloratadine
Manufacturer
Square Pharmaceuticals Ltd.
Country
Bangladesh
Loading images...
Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| nesotem 375 mg tablet | ৳ 12.00 | ৳ 48.00 |
| nesotem 500 mg tablet | ৳ 15.00 | ৳ 150.00 |
Description
Overview of the medicine
Nesotem (Desloratadine) is a non-sedating antihistamine used to relieve symptoms of allergic rhinitis and chronic idiopathic urticaria.
Uses & Indications
Dosage
Adults
5 mg (1 tablet) orally once daily.
Elderly
No specific dosage adjustment required for elderly patients without renal or hepatic impairment.
Renal_impairment
For patients with severe renal impairment (creatinine clearance < 30 mL/min), reduce dosage to 5 mg every other day.
How to Take
Administer orally with or without food.
Mechanism of Action
Selectively blocks peripheral H1 histamine receptors, thereby preventing the effects of histamine.
Pharmacokinetics
Onset
Within 1 hour
Excretion
Excreted equally in urine and feces.
Half life
Approximately 27 hours
Absorption
Rapidly absorbed after oral administration. Peak plasma concentrations are reached in approximately 3 hours.
Metabolism
Extensively metabolized to 3-hydroxydesloratadine, which is also active.
Side Effects
Contraindications
- Known hypersensitivity to desloratadine, loratadine, or any component of the formulation.
- Severe renal impairment without dose adjustment
Drug Interactions
Erythromycin
May increase desloratadine plasma concentrations.
Ketoconazole
May increase desloratadine plasma concentrations.
Storage
Store below 30°C in a dry place, protected from light and moisture. Keep out of reach of children.
Overdose
Symptoms of overdose may include somnolence, increased heart rate, and headache. Management is supportive and symptomatic.
Pregnancy & Lactation
Pregnancy Category C. Use only if potential benefit justifies potential risk to the fetus. Desloratadine passes into breast milk, not recommended during breastfeeding.
Side Effects
Contraindications
- Known hypersensitivity to desloratadine, loratadine, or any component of the formulation.
- Severe renal impairment without dose adjustment
Drug Interactions
Erythromycin
May increase desloratadine plasma concentrations.
Ketoconazole
May increase desloratadine plasma concentrations.
Storage
Store below 30°C in a dry place, protected from light and moisture. Keep out of reach of children.
Overdose
Symptoms of overdose may include somnolence, increased heart rate, and headache. Management is supportive and symptomatic.
Pregnancy & Lactation
Pregnancy Category C. Use only if potential benefit justifies potential risk to the fetus. Desloratadine passes into breast milk, not recommended during breastfeeding.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
24 months
Availability
Pharmacies nationwide
Approval Status
Approved
Patent Status
Expired (generic available)
Clinical Trials
Extensive clinical trials have confirmed the efficacy and safety of desloratadine in allergic rhinitis and chronic idiopathic urticaria across various patient populations.
Lab Monitoring
- No routine lab monitoring required.
- Monitor liver function in patients with pre-existing hepatic impairment.
Doctor Notes
- Advise patients on proper administration and potential side effects.
- Consider renal/hepatic dose adjustment in elderly.
- Educate on avoiding triggers.
Patient Guidelines
- Take once daily as prescribed.
- Do not exceed the recommended dose.
- Inform your doctor about all other medications you are taking.
Missed Dose Advice
Take the missed dose as soon as you remember, unless it is almost time for your next scheduled dose. Do not double the dose.
Driving Precautions
Desloratadine is generally non-sedating. However, individuals should assess their response before driving or operating machinery.
Lifestyle Advice
- Avoid known allergens to reduce symptoms.
- Maintain good hydration.
- Get adequate rest.
Alternative Medicines in Bangladesh
Similar medicines available in the market
Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.
Other Medicines in Nesotem Brand
Other medicines available under the same brand name
