Neugalin
Generic Name
Pregabalin
Manufacturer
Square Pharmaceuticals Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| neugalin 150 mg capsule | ৳ 30.10 | ৳ 301.00 |
Description
Overview of the medicine
Pregabalin is an antiepileptic drug used to treat neuropathic pain, fibromyalgia, and as an adjunct therapy for partial onset seizures in adults.
Uses & Indications
Dosage
Adults
Initial dose 75 mg twice daily or 50 mg three times daily, titrated up to 150-300 mg twice daily (max 600 mg/day). Specific dosage depends on condition.
Elderly
May require lower doses due to potential decreased renal function.
Renal_impairment
Dosage adjustment required based on creatinine clearance.
How to Take
Can be taken with or without food. Swallow capsule whole.
Mechanism of Action
Binds to the alpha2-delta subunit of voltage-gated calcium channels in the central nervous system, reducing the release of several neurotransmitters including glutamate, norepinephrine, and substance P.
Pharmacokinetics
Onset
Within 1 week for pain relief, but can vary.
Excretion
Primarily excreted unchanged in urine.
Half life
Approximately 6.3 hours.
Absorption
Rapidly absorbed after oral administration, bioavailability >90%.
Metabolism
Negligible metabolism in humans; primarily excreted unchanged.
Side Effects
Contraindications
- Hypersensitivity to pregabalin or any component of the formulation
Drug Interactions
CNS Depressants
May enhance the sedative effects of opioids, benzodiazepines, and alcohol. Use with caution.
Thiazolidinediones
May increase the risk of peripheral edema and weight gain when co-administered.
Storage
Store at room temperature (below 30°C), protected from light and moisture. Keep out of reach of children.
Overdose
Symptoms may include somnolence, confusion, agitation, and seizures. Supportive treatment and hemodialysis may be considered.
Pregnancy & Lactation
Use during pregnancy only if the potential benefit outweighs the potential risk to the fetus. Excreted in breast milk, caution advised.
Side Effects
Contraindications
- Hypersensitivity to pregabalin or any component of the formulation
Drug Interactions
CNS Depressants
May enhance the sedative effects of opioids, benzodiazepines, and alcohol. Use with caution.
Thiazolidinediones
May increase the risk of peripheral edema and weight gain when co-administered.
Storage
Store at room temperature (below 30°C), protected from light and moisture. Keep out of reach of children.
Overdose
Symptoms may include somnolence, confusion, agitation, and seizures. Supportive treatment and hemodialysis may be considered.
Pregnancy & Lactation
Use during pregnancy only if the potential benefit outweighs the potential risk to the fetus. Excreted in breast milk, caution advised.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
2-3 years
Availability
Pharmacies, hospitals
Approval Status
Approved
Patent Status
Generic available
Clinical Trials
Ongoing studies for various neuropathic pain conditions and epilepsy.
Lab Monitoring
- Renal function (creatinine clearance) in patients with renal impairment or elderly.
Doctor Notes
- Counsel patients on potential for dizziness and somnolence.
- Emphasize gradual withdrawal to prevent rebound symptoms.
- Monitor for signs of misuse or dependence, especially in patients with a history of substance abuse.
Patient Guidelines
- Do not stop taking this medicine suddenly without consulting your doctor.
- Avoid alcohol while on this medication.
- Report any unusual mood changes or suicidal thoughts to your doctor immediately.
Missed Dose Advice
Take the missed dose as soon as you remember. If it's almost time for the next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.
Driving Precautions
May cause dizziness or somnolence. Patients should be advised not to drive or operate complex machinery until they are sure pregabalin does not affect their ability.
Lifestyle Advice
- Maintain a healthy diet and exercise regimen.
- Avoid activities requiring alertness until you know how the medicine affects you.
Alternative Medicines in Bangladesh
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Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.
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