Nolargy
Generic Name
Fexofenadine Hydrochloride
Manufacturer
Hypothetical Pharma Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| nolargy 30 mg suspension | ৳ 48.00 | N/A |
Description
Overview of the medicine
Nolargy 30 mg Suspension contains Fexofenadine Hydrochloride, a second-generation antihistamine used for the relief of symptoms associated with seasonal allergic rhinitis and chronic idiopathic urticaria. It provides non-sedating relief from sneezing, runny nose, itchy nose/palate/throat, and itchy watery eyes.
Uses & Indications
Dosage
Adults
Typically 60 mg twice daily or 180 mg once daily. For suspension, 30 mg twice daily may be for children or adjusted based on age/weight.
Elderly
No specific dose adjustment is usually required for elderly patients with normal renal function.
Renal_impairment
Initial dose of 60 mg once daily is recommended for adults; for children, dose reduction should be considered.
How to Take
Shake the bottle well before each use. Take orally, with or without food, as directed by a physician. Use the provided measuring device for accurate dosing.
Mechanism of Action
Fexofenadine is a selective peripheral H1-blocker. It binds to H1 receptors and prevents the action of histamine, which is responsible for allergic symptoms, without significantly crossing the blood-brain barrier, thus minimizing sedative effects.
Pharmacokinetics
Onset
Within 1 hour
Excretion
Mainly excreted unchanged in feces (approx. 80%) and urine (approx. 10%).
Half life
Approximately 11-15 hours
Absorption
Rapidly absorbed after oral administration; peak plasma concentrations reached in 1-3 hours.
Metabolism
Minimally metabolized; hepatic metabolism is negligible.
Side Effects
Contraindications
- Hypersensitivity to fexofenadine or any excipients of the formulation
Drug Interactions
Erythromycin or Ketoconazole
May increase fexofenadine plasma concentrations, though clinical significance is minimal.
Antacids containing aluminum or magnesium
May decrease the absorption of fexofenadine. Separate administration by at least 2 hours.
Storage
Store in a cool, dry place, below 30°C. Protect from light and moisture. Keep out of reach of children.
Overdose
Symptoms of overdose include dizziness, drowsiness, and dry mouth. Treatment is symptomatic and supportive. Gastric lavage or activated charcoal may be considered soon after ingestion.
Pregnancy & Lactation
Pregnancy Category C. Use only if potential benefit justifies the potential risk to the fetus. Excreted in breast milk; use with caution in lactating mothers.
Side Effects
Contraindications
- Hypersensitivity to fexofenadine or any excipients of the formulation
Drug Interactions
Erythromycin or Ketoconazole
May increase fexofenadine plasma concentrations, though clinical significance is minimal.
Antacids containing aluminum or magnesium
May decrease the absorption of fexofenadine. Separate administration by at least 2 hours.
Storage
Store in a cool, dry place, below 30°C. Protect from light and moisture. Keep out of reach of children.
Overdose
Symptoms of overdose include dizziness, drowsiness, and dry mouth. Treatment is symptomatic and supportive. Gastric lavage or activated charcoal may be considered soon after ingestion.
Pregnancy & Lactation
Pregnancy Category C. Use only if potential benefit justifies the potential risk to the fetus. Excreted in breast milk; use with caution in lactating mothers.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
24 months from manufacturing date
Availability
Available in pharmacies and hospitals
Approval Status
Approved by relevant authorities (e.g., FDA, DGDA)
Patent Status
Off-patent
Clinical Trials
Fexofenadine has undergone extensive clinical trials demonstrating its efficacy and safety for allergic rhinitis and chronic idiopathic urticaria.
Lab Monitoring
- No routine lab monitoring is generally required. Monitor for symptom relief and adverse effects.
Doctor Notes
- Advise patients to avoid taking with fruit juices.
- Emphasize proper shaking and accurate measurement for pediatric doses.
- Reassure patients about its non-sedating nature, but advise caution if initial doses cause any drowsiness.
Patient Guidelines
- Shake well before each use.
- Use the provided measuring spoon or cup to ensure accurate dosing.
- Do not exceed the recommended dose.
- Store at room temperature away from moisture and heat.
Missed Dose Advice
If a dose is missed, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and resume your regular dosing schedule. Do not double the dose.
Driving Precautions
Fexofenadine is generally non-sedating. However, individuals should assess their response to the medication before driving or operating machinery.
Lifestyle Advice
- Avoid known allergens to prevent triggering allergic reactions.
- Maintain good hydration.
- Avoid alcohol as it may enhance drowsiness (though minimal with fexofenadine).
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