Odafen
Generic Name
Fexofenadine Hydrochloride
Manufacturer
Square Pharmaceuticals Ltd.
Country
Bangladesh
Loading images...
Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| odafen 120 mg tablet | ৳ 8.64 | ৳ 86.40 |
Description
Overview of the medicine
Odafen 120 mg tablet contains Fexofenadine Hydrochloride, a non-sedating second-generation antihistamine used to relieve symptoms of seasonal allergic rhinitis (hay fever) and chronic idiopathic urticaria (hives).
Uses & Indications
Dosage
Adults
For seasonal allergic rhinitis: 120 mg orally once daily. For chronic idiopathic urticaria: 180 mg orally once daily (if available in this strength, otherwise 120mg might be used off-label or for mild cases).
Elderly
No dosage adjustment is generally needed for elderly patients unless they have renal impairment.
Renal_impairment
For patients with impaired renal function, the recommended starting dose is 60 mg orally once daily. Consult a doctor for appropriate dosage.
How to Take
Take Odafen 120 mg tablet orally with water, preferably before a meal. Do not take with fruit juices (e.g., grapefruit, orange, apple) as they may reduce absorption.
Mechanism of Action
Fexofenadine selectively antagonizes peripheral H1-receptors, preventing histamine from binding and causing allergic symptoms like sneezing, runny nose, itchy eyes, and hives. It has minimal penetration into the central nervous system, leading to a low incidence of sedation.
Pharmacokinetics
Onset
Within 1 hour
Excretion
Primarily excreted in the feces (approximately 80%) and urine (approximately 12%) as unchanged drug.
Half life
Approximately 14 hours
Absorption
Rapidly absorbed after oral administration. Peak plasma concentrations are achieved in approximately 2-3 hours.
Metabolism
Minimally metabolized; approximately 5% of a dose is metabolized.
Side Effects
Contraindications
- •Hypersensitivity to fexofenadine or any of its excipients.
Drug Interactions
Other antihistamines
Avoid concomitant use with other antihistamines, especially sedating ones, to prevent additive effects.
Erythromycin and Ketoconazole
Can increase plasma levels of fexofenadine; however, no increase in adverse effects has been observed in clinical trials.
Antacids (aluminum and magnesium containing)
May reduce the absorption of fexofenadine. It is advisable to separate the administration by at least 2 hours.
Storage
Store below 30°C in a dry place, away from light and moisture. Keep out of reach of children.
Overdose
Symptoms of overdose may include dizziness, drowsiness, and dry mouth. In case of an overdose, symptomatic and supportive treatment is recommended. Hemodialysis does not effectively remove fexofenadine from blood.
Pregnancy & Lactation
Pregnancy Category C. Use during pregnancy only if the potential benefit justifies the potential risk to the fetus. Fexofenadine is excreted in human breast milk; therefore, caution should be exercised when administered to a nursing woman.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
2 to 3 years from the date of manufacture, specific details on packaging.
Availability
Available in pharmacies and hospitals
Approval Status
Approved (DGDA)
Patent Status
Generic (Patent Expired)
WHO Essential Medicine
YesAlternative Medicines in Bangladesh
Similar medicines available in the market
Global Brand Names
International brand names for this medicine
More Medicines
Explore other medicines you might be interested in
