Oxycort
Generic Name
Budesonide
Manufacturer
Square Pharmaceuticals Ltd.
Country
Bangladesh
Loading images...
Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| oxycort 200 mcg inhalation capsule | ৳ 11.00 | ৳ 110.00 |
Description
Overview of the medicine
Budesonide is an inhaled corticosteroid used to manage asthma and COPD. It reduces inflammation in the airways, making breathing easier.
Uses & Indications
Dosage
Adults
Asthma: 200-400 mcg twice daily. COPD: 200 mcg twice daily. Dosage adjusted based on individual response.
Elderly
No specific dose adjustment required, but monitor for systemic corticosteroid effects, especially with higher doses.
Renal_impairment
No specific dose adjustment required. Budesonide is primarily metabolized by the liver.
How to Take
Administered via a dry powder inhaler device. The capsule should be placed in the device, and the patient should inhale deeply and steadily through the mouthpiece. Do not swallow the capsule. Rinse mouth with water after each use.
Mechanism of Action
Budesonide acts locally in the lungs as a potent glucocorticoid. It binds to glucocorticoid receptors, inhibiting the release of inflammatory mediators and suppressing immune cell function, thereby reducing airway inflammation and hyperresponsiveness.
Pharmacokinetics
Onset
Onset of action within hours; full therapeutic effect usually seen within 1-2 weeks of regular use.
Excretion
Primarily excreted in urine and feces as metabolites.
Half life
Approximately 2-3 hours (systemic plasma half-life).
Absorption
Rapidly absorbed from the lungs. Systemic bioavailability is low due to extensive first-pass metabolism in the liver.
Metabolism
Extensively metabolized in the liver by CYP3A4 to inactive metabolites.
Side Effects
Contraindications
- Hypersensitivity to Budesonide or any component of the formulation.
- Acute bronchospasm (Budesonide is not indicated for rapid relief of bronchospasm).
Drug Interactions
Other Inhaled Corticosteroids
Increased risk of systemic corticosteroid effects if used concurrently with other systemic or inhaled corticosteroids.
Strong CYP3A4 Inhibitors (e.g., Ketoconazole, Itraconazole, Ritonavir)
May significantly increase plasma levels of Budesonide, potentially leading to systemic corticosteroid effects. Concomitant administration should be avoided or dose adjusted with careful monitoring.
Storage
Store below 30°C in a dry place, protected from light and moisture. Keep out of reach of children.
Overdose
Acute overdose is unlikely to cause clinically significant problems. Chronic overdose may lead to systemic corticosteroid effects (e.g., Cushing's syndrome, adrenal suppression). Management involves gradual reduction of dosage and supportive care.
Pregnancy & Lactation
Pregnancy Category B. Use only if the potential benefit outweighs the potential risk. Budesonide is generally considered safe during lactation as minimal transfer into breast milk occurs.
Side Effects
Contraindications
- Hypersensitivity to Budesonide or any component of the formulation.
- Acute bronchospasm (Budesonide is not indicated for rapid relief of bronchospasm).
Drug Interactions
Other Inhaled Corticosteroids
Increased risk of systemic corticosteroid effects if used concurrently with other systemic or inhaled corticosteroids.
Strong CYP3A4 Inhibitors (e.g., Ketoconazole, Itraconazole, Ritonavir)
May significantly increase plasma levels of Budesonide, potentially leading to systemic corticosteroid effects. Concomitant administration should be avoided or dose adjusted with careful monitoring.
Storage
Store below 30°C in a dry place, protected from light and moisture. Keep out of reach of children.
Overdose
Acute overdose is unlikely to cause clinically significant problems. Chronic overdose may lead to systemic corticosteroid effects (e.g., Cushing's syndrome, adrenal suppression). Management involves gradual reduction of dosage and supportive care.
Pregnancy & Lactation
Pregnancy Category B. Use only if the potential benefit outweighs the potential risk. Budesonide is generally considered safe during lactation as minimal transfer into breast milk occurs.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
24-36 months from manufacturing date.
Availability
Pharmacies, hospitals
Approval Status
Approved by major regulatory bodies (e.g., FDA, EMA, DGDA)
Patent Status
Generic available
WHO Essential Medicine
YesClinical Trials
Extensive clinical trials have demonstrated the efficacy and safety of Budesonide in the long-term management of asthma and COPD across various patient populations.
Lab Monitoring
- Regular monitoring of lung function (FEV1) in asthma/COPD patients.
- Adrenal function tests may be considered if high doses are used for prolonged periods.
- Growth monitoring in children.
Doctor Notes
- Educate patients on proper inhaler technique and the importance of rinsing the mouth post-use.
- Monitor for signs of oral candidiasis and systemic corticosteroid effects, especially in patients on high doses or concomitant systemic corticosteroids.
- Emphasize that this is a controller medication, not a rescue inhaler.
Patient Guidelines
- Always follow the prescribed dosage and administration instructions.
- Rinse your mouth with water after each dose to help prevent oral candidiasis.
- This medicine is for maintenance treatment, not for sudden breathing difficulties.
- Do not stop using this medicine suddenly without consulting your doctor.
Missed Dose Advice
If a dose is missed, take it as soon as remembered. If it is almost time for the next dose, skip the missed dose and resume your regular dosing schedule. Do not take a double dose to make up for a missed one.
Driving Precautions
Budesonide inhalation capsules are not expected to affect the ability to drive or operate machinery.
Lifestyle Advice
- Avoid known triggers that worsen your asthma or COPD (e.g., smoke, allergens).
- Maintain a healthy lifestyle, including regular exercise and a balanced diet, to support overall respiratory health.
Alternative Medicines in Bangladesh
Similar medicines available in the market
Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.
Other Medicines in Oxycort Brand
Other medicines available under the same brand name
