Prex-3
Generic Name
Cefixime
Manufacturer
Hypothetical Pharma Ltd.
Country
Bangladesh
Loading images...
Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| prex 3 100 mg suspension | ৳ 125.00 | N/A |
Description
Overview of the medicine
Prex-3 100 mg Suspension is a broad-spectrum antibiotic used to treat a variety of bacterial infections.
Uses & Indications
Dosage
Adults
200-400 mg once daily or 100-200 mg twice daily, for 7-14 days.
Elderly
No specific dose adjustment required unless severe renal impairment.
Renal_impairment
Dose adjustment required; e.g., CrCl < 60 mL/min, reduce dose to 75%.
How to Take
Shake well before use. Can be taken with or without food. Complete the full course of treatment.
Mechanism of Action
Inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs).
Pharmacokinetics
Onset
Peak plasma concentration within 2-6 hours.
Excretion
Renal excretion (approximately 50-60% unchanged in urine), non-renal elimination.
Half life
Average 3-4 hours.
Absorption
Approximately 40-50% orally absorbed, food may delay but not significantly affect absorption.
Metabolism
Not extensively metabolized; primarily excreted unchanged.
Side Effects
Contraindications
- Hypersensitivity to cefixime or other cephalosporins.
- History of severe penicillin allergy.
Drug Interactions
Warfarin
May increase prothrombin time (INR); monitor closely.
Carbamazepine
Increased carbamazepine levels.
Oral Contraceptives
May reduce efficacy; advise backup contraception.
Storage
Store below 30°C. Protect from light and moisture. Keep reconstituted suspension in refrigerator (2-8°C).
Overdose
Gastric lavage may be indicated. No specific antidote. Symptomatic and supportive treatment.
Pregnancy & Lactation
Use in pregnancy only if clearly needed. Excreted in breast milk, use with caution during lactation.
Side Effects
Contraindications
- Hypersensitivity to cefixime or other cephalosporins.
- History of severe penicillin allergy.
Drug Interactions
Warfarin
May increase prothrombin time (INR); monitor closely.
Carbamazepine
Increased carbamazepine levels.
Oral Contraceptives
May reduce efficacy; advise backup contraception.
Storage
Store below 30°C. Protect from light and moisture. Keep reconstituted suspension in refrigerator (2-8°C).
Overdose
Gastric lavage may be indicated. No specific antidote. Symptomatic and supportive treatment.
Pregnancy & Lactation
Use in pregnancy only if clearly needed. Excreted in breast milk, use with caution during lactation.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
24 months for unopened bottle. 7 days after reconstitution.
Availability
Pharmacies, Hospitals
Approval Status
Approved by regulatory authorities (e.g., FDA, DGDA)
Patent Status
Generic available
WHO Essential Medicine
YesClinical Trials
Extensive clinical trials have demonstrated efficacy and safety in various bacterial infections.
Lab Monitoring
- Renal function tests (e.g., creatinine, BUN) if long-term or high dose.
- Liver function tests (e.g., ALT, AST) if signs of hepatic impairment.
- Prothrombin time (INR) if co-administered with anticoagulants.
Doctor Notes
- Counsel patients on completing the full course to prevent resistance.
- Be aware of potential cross-reactivity in penicillin-allergic patients.
Patient Guidelines
- Complete the entire course of medication, even if symptoms improve.
- Do not share this medicine with others.
- Report any severe or persistent side effects to your doctor.
Missed Dose Advice
Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue your regular dosing schedule. Do not double the dose.
Driving Precautions
May cause dizziness; use caution when driving or operating machinery until you know how it affects you.
Lifestyle Advice
- Maintain good hydration.
- Avoid alcohol during treatment.
Alternative Medicines in Bangladesh
Similar medicines available in the market
Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.
Other Medicines in Prex-3 Brand
Other medicines available under the same brand name
