Sergel

Take one tablet orally, usually once daily, at least one hour before a meal. Swallow the tablet whole; do not chew or crush it. If you have difficulty swallowing, disperse the tablet in a glass of non-carbonated water and drink it within 30 minutes.

Esomeprazole selectively inhibits the H+/K+-ATPase (proton pump) in the parietal cells of the stomach, thereby blocking the final step of acid secretion. This leads to a profound and prolonged reduction of gastric acid secretion.

• Hypersensitivity to esomeprazole, substituted benzimidazoles, or any component of the formulation.
• Concomitant use with nelfinavir (an antiretroviral drug).

Store in a cool, dry place below 30°C. Protect from light and moisture. Keep out of reach of children.

Symptoms of overdose are generally mild and self-limiting (e.g., gastrointestinal symptoms, headache). No specific antidote is known. Treatment should be symptomatic and supportive.

Pregnancy Category B. Studies in animals have not shown harm to the fetus, but there are no adequate and well-controlled studies in pregnant women. Use during pregnancy only if clearly needed. Esomeprazole is likely excreted in human milk; caution should be exercised when administered to a nursing woman.

• Hypersensitivity to esomeprazole, substituted benzimidazoles, or any component of the formulation.
• Concomitant use with nelfinavir (an antiretroviral drug).

Store in a cool, dry place below 30°C. Protect from light and moisture. Keep out of reach of children.

Symptoms of overdose are generally mild and self-limiting (e.g., gastrointestinal symptoms, headache). No specific antidote is known. Treatment should be symptomatic and supportive.

Pregnancy Category B. Studies in animals have not shown harm to the fetus, but there are no adequate and well-controlled studies in pregnant women. Use during pregnancy only if clearly needed. Esomeprazole is likely excreted in human milk; caution should be exercised when administered to a nursing woman.