Silox
Generic Name
Simeticone
Manufacturer
ACME Laboratories Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| silox 125 mg suspension | ৳ 60.22 | N/A |
Description
Overview of the medicine
Silox 125 mg Suspension contains Simeticone, an anti-foaming agent used to relieve symptoms of excess gas in the digestive tract. It works by breaking down gas bubbles, making them easier to pass. It is commonly used for bloating, fullness, and discomfort caused by trapped gas.
Uses & Indications
Dosage
Adults
125-250 mg (1-2 spoonfuls of 125 mg/5 ml suspension) four times daily after meals and at bedtime, or as directed by a physician. Do not exceed 500 mg in 24 hours without medical advice.
Elderly
No specific dosage adjustment is generally required for elderly patients.
Renal_impairment
No dosage adjustment is needed as simeticone is not absorbed systemically.
How to Take
Silox Suspension is for oral administration. Shake the bottle well before each use. It can be taken directly or mixed with a small amount of water or other liquid. For infants, it can be added to the feeding bottle.
Mechanism of Action
Simeticone works by altering the surface tension of gas bubbles in the gastrointestinal tract, causing them to coalesce into larger bubbles that are easier to pass or absorb. It acts as an anti-foaming agent, reducing the amount of gas trapped in the stomach and intestines.
Pharmacokinetics
Onset
Relief of symptoms typically occurs within minutes to an hour after administration.
Excretion
Excreted unchanged in the feces.
Half life
Not applicable as it is not absorbed systemically.
Absorption
Simeticone is not absorbed from the gastrointestinal tract into the bloodstream.
Metabolism
Not metabolized in the body.
Side Effects
Contraindications
- Hypersensitivity to simeticone or any component of the formulation.
- Suspected or known intestinal obstruction.
- Perforated or suspected perforated bowel.
Drug Interactions
Thyroid hormones (e.g., Levothyroxine)
Simeticone may interfere with the absorption of thyroid hormones if taken concomitantly. Administer these medications at separate times (at least 4 hours apart).
Storage
Store at room temperature (below 30°C), protected from light and moisture. Keep out of reach of children.
Overdose
Simeticone has very low toxicity due to its lack of systemic absorption. Overdose is unlikely to cause serious adverse effects. In case of accidental ingestion of very large amounts, seek medical advice if any unusual symptoms occur.
Pregnancy & Lactation
Simeticone is generally considered safe for use during pregnancy and lactation as it is not absorbed systemically. However, consult a healthcare professional before use.
Side Effects
Contraindications
- Hypersensitivity to simeticone or any component of the formulation.
- Suspected or known intestinal obstruction.
- Perforated or suspected perforated bowel.
Drug Interactions
Thyroid hormones (e.g., Levothyroxine)
Simeticone may interfere with the absorption of thyroid hormones if taken concomitantly. Administer these medications at separate times (at least 4 hours apart).
Storage
Store at room temperature (below 30°C), protected from light and moisture. Keep out of reach of children.
Overdose
Simeticone has very low toxicity due to its lack of systemic absorption. Overdose is unlikely to cause serious adverse effects. In case of accidental ingestion of very large amounts, seek medical advice if any unusual symptoms occur.
Pregnancy & Lactation
Simeticone is generally considered safe for use during pregnancy and lactation as it is not absorbed systemically. However, consult a healthcare professional before use.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
Typically 2-3 years when stored properly. Refer to the expiry date on the packaging.
Availability
Pharmacies, Supermarkets
Approval Status
Approved
Patent Status
Off-patent
Clinical Trials
Simeticone has been widely studied for its efficacy in relieving gas symptoms, often showing significant improvement compared to placebo. It is generally well-tolerated in various patient populations, including infants.
Lab Monitoring
- No specific laboratory monitoring is required for simeticone.
Doctor Notes
- Educate patients on dietary and lifestyle modifications to prevent recurrent gas.
- Differentiate gas symptoms from other serious gastrointestinal conditions.
- Advise parents/caregivers on proper infant feeding techniques to minimize air swallowing.
Patient Guidelines
- Shake the bottle well before each use to ensure proper mixing.
- Use the measuring spoon or dropper provided with the suspension for accurate dosing.
- Do not exceed the recommended dose without consulting a doctor.
- If symptoms persist for more than a few days or worsen, consult your doctor.
Missed Dose Advice
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and resume your regular dosing schedule. Do not double the dose to catch up.
Driving Precautions
Simeticone is not known to affect the ability to drive or operate machinery.
Lifestyle Advice
- Avoid foods and drinks that are known to cause gas (e.g., beans, cabbage, carbonated drinks).
- Eat slowly and avoid gulping food to minimize air swallowing.
- Regular exercise can help improve digestion and reduce gas.
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