Specbac
Generic Name
Spectramycin 500 mg Injection
Manufacturer
Alpha Pharmaceuticals Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| specbac 500 mg injection | ৳ 700.00 | N/A |
Description
Overview of the medicine
Specbac 500 mg Injection is a broad-spectrum antibiotic used to treat a wide range of bacterial infections, including respiratory tract infections, urinary tract infections, skin and soft tissue infections, and intra-abdominal infections. It is administered intravenously.
Uses & Indications
Dosage
Adults
500 mg IV every 8-12 hours, depending on severity of infection. Duration depends on the type and severity of infection.
Elderly
No specific dose adjustment typically required, but monitor renal function and adjust if impairment is present.
Renal_impairment
Dosage adjustment necessary for severe renal impairment (e.g., reduce to 250 mg every 12-24 hours) based on creatinine clearance.
How to Take
Administer intravenously over 30-60 minutes. Do not administer as a bolus injection. Reconstitute with appropriate diluent (e.g., Water for Injection) as per manufacturer's instructions. Ensure aseptic technique.
Mechanism of Action
Spectramycin inhibits bacterial protein synthesis by binding to the 50S ribosomal subunit, thereby preventing peptide chain elongation and bacterial growth.
Pharmacokinetics
Onset
Within 15-30 minutes.
Excretion
Primarily excreted unchanged via kidneys.
Half life
Approximately 2-3 hours.
Absorption
Rapid and complete absorption following intravenous administration.
Metabolism
Minimal hepatic metabolism.
Side Effects
Contraindications
- •Hypersensitivity to Spectramycin or any component of the formulation
- •History of severe allergic reactions to other antibiotics of similar class (e.g., other novel antibacterial agents)
Drug Interactions
Warfarin
Concomitant use may enhance the anticoagulant effect of Warfarin. Monitor INR closely and adjust Warfarin dose as needed.
Probenecid
Probenecid may increase Spectramycin plasma concentrations by reducing renal tubular secretion.
Aminoglycosides
Increased risk of nephrotoxicity when Spectramycin is used concurrently with aminoglycosides. Monitor renal function.
Storage
Store below 30°C in a dry place, protected from direct light and moisture. Do not freeze. Keep out of reach and sight of children. Reconstituted solution should be used immediately or within 6 hours if refrigerated.
Overdose
In case of overdose, discontinue the drug immediately and provide symptomatic and supportive treatment. There is no specific antidote. Hemodialysis may be considered in severe cases to aid in drug removal from the bloodstream.
Pregnancy & Lactation
Pregnancy Category B. Studies in animals have shown no evidence of harm to the fetus, but adequate and well-controlled studies in pregnant women are lacking. Use with caution during pregnancy if clearly needed. Spectramycin is excreted in breast milk; use with caution during lactation after assessing potential risks vs. benefits.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
36 months from manufacturing date when stored correctly.
Availability
Available in hospitals, clinics, and retail pharmacies
Approval Status
Approved by DGDA
Patent Status
Patented (expiry 2030)
WHO Essential Medicine
YesAlternative Medicines in Bangladesh
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Global Brand Names
International brand names for this medicine
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