Sporin
Generic Name
Polymyxin B Sulfate, Neomycin Sulfate, Bacitracin Zinc
Manufacturer
Various manufacturers
Country
Global
Loading images...
Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| sporin 500 mg capsule | ৳ 12.00 | N/A |
| sporin 125 mg suspension | ৳ 80.00 | N/A |
| sporin 125 mg pediatric drop | ৳ 60.00 | N/A |
Description
Overview of the medicine
Sporin is a topical antibiotic ointment containing Polymyxin B, Neomycin, and Bacitracin Zinc. It is used to prevent and treat minor skin infections caused by susceptible bacteria.
Uses & Indications
Dosage
Adults
Apply a small amount to the affected area 1 to 3 times daily.
Elderly
Same as adult dosage.
Renal_impairment
No dosage adjustment needed for topical use.
How to Take
Clean the affected area before application. Apply a thin layer and gently rub it in. May be covered with a sterile bandage.
Mechanism of Action
Polymyxin B and Bacitracin inhibit bacterial cell wall synthesis and damage the bacterial cell membrane, while Neomycin interferes with bacterial protein synthesis. Together, they provide broad-spectrum antibacterial activity.
Pharmacokinetics
Onset
Local antibacterial effect starts shortly after application.
Excretion
Systemic excretion is negligible with topical application.
Half life
Not applicable for topical use due to minimal systemic absorption.
Absorption
Minimal systemic absorption through intact skin. Increased absorption may occur through broken skin or mucous membranes.
Metabolism
Systemic metabolism is negligible with topical application.
Side Effects
Contraindications
- Hypersensitivity to Polymyxin B, Neomycin, Bacitracin, or any component of the formulation
- Extensive skin damage or deep puncture wounds (risk of systemic absorption and ototoxicity/nephrotoxicity with Neomycin)
Drug Interactions
Other topical preparations
May interfere with the effectiveness of other topical preparations applied concurrently.
No significant systemic interactions
No significant systemic drug interactions expected with topical application.
Storage
Store below 30°C. Protect from light and moisture. Keep out of reach of children.
Overdose
Topical overdose is unlikely to cause systemic effects. Excessive application may lead to local irritation. If ingested, seek medical attention.
Pregnancy & Lactation
Generally considered safe for topical use during pregnancy and lactation, but consult a doctor. Avoid applying to large areas or broken skin.
Side Effects
Contraindications
- Hypersensitivity to Polymyxin B, Neomycin, Bacitracin, or any component of the formulation
- Extensive skin damage or deep puncture wounds (risk of systemic absorption and ototoxicity/nephrotoxicity with Neomycin)
Drug Interactions
Other topical preparations
May interfere with the effectiveness of other topical preparations applied concurrently.
No significant systemic interactions
No significant systemic drug interactions expected with topical application.
Storage
Store below 30°C. Protect from light and moisture. Keep out of reach of children.
Overdose
Topical overdose is unlikely to cause systemic effects. Excessive application may lead to local irritation. If ingested, seek medical attention.
Pregnancy & Lactation
Generally considered safe for topical use during pregnancy and lactation, but consult a doctor. Avoid applying to large areas or broken skin.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
24-36 months
Availability
Pharmacies, drugstores
Approval Status
Approved by FDA and DGDA
Patent Status
Off-patent
Clinical Trials
Numerous clinical studies have supported the efficacy and safety of Polymyxin B, Neomycin, and Bacitracin in combination for topical skin infections over decades.
Lab Monitoring
- Not required for topical use.
Doctor Notes
- Advise patients on proper hygiene and wound care.
- Educate on signs of allergic reaction or worsening infection.
- Remind patients that this is for external use only.
Patient Guidelines
- Use only as directed by a healthcare professional.
- Wash hands before and after applying the ointment.
- Avoid contact with eyes, nose, and mouth.
- Do not use for more than one week unless directed by a doctor.
Missed Dose Advice
If you miss a dose, apply it as soon as you remember. Do not apply extra to make up for a missed dose.
Driving Precautions
No known effects on driving or operating machinery.
Lifestyle Advice
- Keep the affected area clean and dry.
- Avoid scratching the infected area.
Alternative Medicines in Bangladesh
Similar medicines available in the market
Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.
Other Medicines in Sporin Brand
Other medicines available under the same brand name
