Oral, preferably with food or milk to minimize gastrointestinal upset.

Starin inhibits cyclooxygenase (COX-1 and COX-2) enzymes, which are responsible for the synthesis of prostaglandins. Prostaglandins are mediators of pain, inflammation, and fever, thereby reducing these symptoms.

• •Hypersensitivity to Starin or other NSAIDs
• •Active peptic ulcer or gastrointestinal bleeding
• •Severe renal or hepatic impairment
• •Third trimester of pregnancy
• •Severe heart failure

Store in a cool, dry place, below 30°C. Protect from light and moisture. Keep out of reach of children.

Symptoms may include nausea, vomiting, epigastric pain, headache, drowsiness. Management involves symptomatic and supportive care. Gastric lavage and activated charcoal may be considered within the first hour.

Avoid during the third trimester of pregnancy due to risk of premature closure of the ductus arteriosus. Use with caution during first and second trimesters and during lactation, only if benefits outweigh risks and under medical supervision.