Superpime
Generic Name
Cefepime
Manufacturer
Beximco Pharmaceuticals Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| superpime 1 gm injection | ৳ 551.64 | N/A |
| superpime 500 mg injection | ৳ 300.90 | N/A |
Description
Overview of the medicine
Cefepime is a fourth-generation cephalosporin antibiotic used to treat a wide variety of bacterial infections, including pneumonia, urinary tract infections, skin and soft tissue infections, and febrile neutropenia.
Uses & Indications
Dosage
Adults
1-2 g IV every 8-12 hours.
Elderly
Dose adjustment based on renal function.
Renal_impairment
Reduced dosage required based on creatinine clearance.
How to Take
Administered intravenously (IV) or intramuscularly (IM) after reconstitution.
Mechanism of Action
Inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs).
Pharmacokinetics
Onset
Within minutes for IV, 1-2 hours for IM.
Excretion
Primarily renal excretion (85% unchanged drug in urine).
Half life
Approximately 2 hours.
Absorption
Rapidly and completely absorbed after IM/IV administration.
Metabolism
Minimal hepatic metabolism.
Side Effects
Contraindications
- Hypersensitivity to cefepime or other beta-lactam antibiotics.
Drug Interactions
Loop Diuretics
May increase cefepime levels.
Aminoglycosides
Increased risk of nephrotoxicity.
Storage
Store below 30°C in a dry place, away from light. Keep out of reach of children.
Overdose
Symptoms include encephalopathy, seizures, and neuromuscular excitability. Management involves supportive care and hemodialysis.
Pregnancy & Lactation
Use with caution; consult a doctor. Cefepime is generally considered safe in pregnancy (Category B) and excreted in low amounts into breast milk.
Side Effects
Contraindications
- Hypersensitivity to cefepime or other beta-lactam antibiotics.
Drug Interactions
Loop Diuretics
May increase cefepime levels.
Aminoglycosides
Increased risk of nephrotoxicity.
Storage
Store below 30°C in a dry place, away from light. Keep out of reach of children.
Overdose
Symptoms include encephalopathy, seizures, and neuromuscular excitability. Management involves supportive care and hemodialysis.
Pregnancy & Lactation
Use with caution; consult a doctor. Cefepime is generally considered safe in pregnancy (Category B) and excreted in low amounts into breast milk.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
24-36 months
Availability
Pharmacies, Hospitals
Approval Status
Approved by DGDA
Patent Status
Generic available
WHO Essential Medicine
YesClinical Trials
Extensive clinical trials support its efficacy and safety in various infections.
Lab Monitoring
- Renal function tests (creatinine, BUN)
- Liver function tests
- Complete blood count
Doctor Notes
- Monitor renal function in elderly and renally impaired patients. Adjust dose accordingly. Be aware of potential neurological adverse effects, especially with high doses in patients with renal dysfunction.
Patient Guidelines
- Complete the full course of treatment.
- Do not share this medicine with others.
- Inform your doctor about any allergies.
Missed Dose Advice
Take the missed dose as soon as remembered. If it's almost time for the next dose, skip the missed dose and resume regular schedule.
Driving Precautions
May cause dizziness; avoid driving or operating heavy machinery if affected.
Lifestyle Advice
- Maintain good hygiene to prevent further infections.
- Stay hydrated.
Alternative Medicines in Bangladesh
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Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.
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