Telfast
Generic Name
Fexofenadine
Manufacturer
Sanofi
Country
France
Loading images...
Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| telfast 120 mg tablet | ৳ 10.00 | ৳ 100.00 |
| telfast 180 mg tablet | ৳ 13.00 | ৳ 130.00 |
| telfast 30 mg suspension | ৳ 70.00 | N/A |
Description
Overview of the medicine
Telfast is an antihistamine used to relieve symptoms of seasonal allergic rhinitis (hay fever) and chronic idiopathic urticaria (hives). It helps alleviate symptoms like sneezing, runny nose, itchy eyes/nose/throat, and skin rash/itching.
Uses & Indications
Dosage
Adults
For seasonal allergic rhinitis: 120 mg or 180 mg once daily. For chronic idiopathic urticaria: 180 mg once daily.
Elderly
No specific dose adjustment is generally required for elderly patients with normal renal function.
Renal_impairment
For adults and children 12 years and older with impaired renal function, a starting dose of 60 mg once daily is recommended.
How to Take
Telfast tablets should be taken orally with water, preferably before a meal. Do not take with fruit juices.
Mechanism of Action
Fexofenadine, the active ingredient in Telfast, is a selective peripheral H1-receptor antagonist. It blocks the action of histamine, a natural substance in the body that causes allergic symptoms, without significant sedation or anticholinergic effects.
Pharmacokinetics
Onset
Onset of action typically occurs within 1-3 hours.
Excretion
Primarily excreted unchanged in feces (approximately 80%) and urine (approximately 11%).
Half life
The elimination half-life is approximately 11-15 hours.
Absorption
Rapidly absorbed after oral administration, with peak plasma concentrations reached in approximately 1-3 hours.
Metabolism
Minimally metabolized; approximately 5% of the total dose is metabolized in the liver.
Side Effects
Contraindications
- Hypersensitivity to fexofenadine or any components of the formulation.
Drug Interactions
Erythromycin and Ketoconazole
These drugs have been shown to increase fexofenadine plasma concentrations, though clinical significance is generally minimal.
Antacids (aluminum and magnesium hydroxide)
Concomitant administration of antacids containing aluminum and magnesium hydroxide within 15 minutes of Telfast significantly reduces fexofenadine bioavailability. It is recommended to separate administration by at least 2 hours.
Storage
Store below 30°C in a dry place, protected from light and moisture. Keep out of reach of children.
Overdose
Symptoms of overdose may include drowsiness, dizziness, and dry mouth. Management involves symptomatic and supportive treatment; there is no specific antidote.
Pregnancy & Lactation
Pregnancy Category C. Use during pregnancy only if the potential benefit justifies the potential risk to the fetus. Fexofenadine is excreted in human milk; caution should be exercised when administered to a nursing woman.
Side Effects
Contraindications
- Hypersensitivity to fexofenadine or any components of the formulation.
Drug Interactions
Erythromycin and Ketoconazole
These drugs have been shown to increase fexofenadine plasma concentrations, though clinical significance is generally minimal.
Antacids (aluminum and magnesium hydroxide)
Concomitant administration of antacids containing aluminum and magnesium hydroxide within 15 minutes of Telfast significantly reduces fexofenadine bioavailability. It is recommended to separate administration by at least 2 hours.
Storage
Store below 30°C in a dry place, protected from light and moisture. Keep out of reach of children.
Overdose
Symptoms of overdose may include drowsiness, dizziness, and dry mouth. Management involves symptomatic and supportive treatment; there is no specific antidote.
Pregnancy & Lactation
Pregnancy Category C. Use during pregnancy only if the potential benefit justifies the potential risk to the fetus. Fexofenadine is excreted in human milk; caution should be exercised when administered to a nursing woman.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
Typically 2-3 years from the date of manufacture, specific to batch.
Availability
Pharmacies
Approval Status
Approved by FDA/DGDA
Patent Status
Expired
Clinical Trials
Fexofenadine has undergone extensive clinical trials demonstrating its efficacy and safety in treating seasonal allergic rhinitis and chronic idiopathic urticaria, showing superior efficacy to placebo and comparable to other antihistamines with a favorable safety profile.
Lab Monitoring
- No routine lab monitoring is generally required for Telfast.
Doctor Notes
- Emphasize the non-sedating nature of fexofenadine, making it suitable for patients needing to remain alert.
- Advise patients about the critical interaction with fruit juices and antacids, recommending separation of administration times.
- Consider dosage adjustment for patients with renal impairment.
Patient Guidelines
- Do not exceed the recommended dose.
- Avoid taking with fruit juices.
- Inform your doctor about all other medications you are taking.
Missed Dose Advice
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.
Driving Precautions
Telfast is generally non-sedating, but individual responses vary. Patients should exercise caution when driving or operating machinery until they know how Telfast affects them.
Lifestyle Advice
- Identify and avoid known allergens.
- Maintain good indoor air quality.
- Stay hydrated.
Alternative Medicines in Bangladesh
Similar medicines available in the market
Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.
Other Medicines in Telfast Brand
Other medicines available under the same brand name
