Telfex
Generic Name
Fexofenadine Hydrochloride
Manufacturer
Square Pharmaceuticals Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| telfex 120 mg tablet | ৳ 8.00 | ৳ 80.00 |
Description
Overview of the medicine
Telfex 120 mg tablet contains Fexofenadine Hydrochloride, a non-sedating antihistamine used to relieve symptoms of seasonal allergic rhinitis (hay fever) and chronic idiopathic urticaria (hives). It helps alleviate sneezing, runny nose, itchy watery eyes, and itchy skin rashes.
Uses & Indications
Dosage
Adults
For seasonal allergic rhinitis: 120 mg once daily. For chronic idiopathic urticaria: 180 mg once daily (use Telfex 180 mg if available).
Elderly
No dosage adjustment is generally required for elderly patients with normal renal function.
Renal_impairment
For adults with impaired renal function, the recommended starting dose is 60 mg once daily.
How to Take
Take the tablet orally with water, preferably before a meal. Do not take with fruit juices (e.g., grapefruit, orange, apple juice) as they may reduce absorption.
Mechanism of Action
Fexofenadine is a selective peripheral H1-receptor antagonist. It works by blocking the action of histamine, a natural substance in the body that causes allergic symptoms. By blocking H1 receptors, it prevents histamine from binding and causing symptoms like sneezing, itching, and watery eyes, without causing significant drowsiness.
Pharmacokinetics
Onset
Within 1 hour.
Excretion
Primarily excreted unchanged via feces (approximately 80%) and urine (approximately 11%).
Half life
Approximately 11-15 hours.
Absorption
Rapidly absorbed after oral administration. Peak plasma concentrations are reached in 1-3 hours.
Metabolism
Minimally metabolized; approximately 5% of the total dose is metabolized.
Side Effects
Contraindications
- Known hypersensitivity to fexofenadine or any components of the tablet.
Drug Interactions
Erythromycin and Ketoconazole
Can increase plasma levels of fexofenadine, but this is generally not associated with increased adverse effects.
Antacids (aluminum and magnesium hydroxide containing)
May reduce the absorption of fexofenadine. Separate administration by about 2 hours.
Storage
Store in a cool, dry place below 30°C. Protect from light and moisture. Keep out of reach of children.
Overdose
Symptoms of overdose include drowsiness, dizziness, and dry mouth. Management should be symptomatic and supportive, including measures to remove unabsorbed drug and standard supportive therapy.
Pregnancy & Lactation
Pregnancy Category C. Use only if the potential benefit justifies the potential risk to the fetus. Fexofenadine is excreted in human breast milk; caution should be exercised when administered to a nursing woman.
Side Effects
Contraindications
- Known hypersensitivity to fexofenadine or any components of the tablet.
Drug Interactions
Erythromycin and Ketoconazole
Can increase plasma levels of fexofenadine, but this is generally not associated with increased adverse effects.
Antacids (aluminum and magnesium hydroxide containing)
May reduce the absorption of fexofenadine. Separate administration by about 2 hours.
Storage
Store in a cool, dry place below 30°C. Protect from light and moisture. Keep out of reach of children.
Overdose
Symptoms of overdose include drowsiness, dizziness, and dry mouth. Management should be symptomatic and supportive, including measures to remove unabsorbed drug and standard supportive therapy.
Pregnancy & Lactation
Pregnancy Category C. Use only if the potential benefit justifies the potential risk to the fetus. Fexofenadine is excreted in human breast milk; caution should be exercised when administered to a nursing woman.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
24-36 months from the date of manufacture, specific to manufacturer's instructions.
Availability
Available in pharmacies nationwide
Approval Status
Approved (in Bangladesh by DGDA)
Patent Status
Patent expired, generic versions available
Clinical Trials
Fexofenadine has undergone extensive clinical trials demonstrating its efficacy and safety in treating seasonal allergic rhinitis and chronic idiopathic urticaria.
Lab Monitoring
- Generally, no specific laboratory monitoring is required for patients taking fexofenadine.
Doctor Notes
- Fexofenadine is a preferred second-generation antihistamine due to its non-sedating profile and efficacy.
- Advise patients to avoid taking with fruit juices.
- Consider dosage adjustment in patients with renal impairment.
Patient Guidelines
- Take exactly as prescribed by your doctor.
- Do not exceed the recommended dose.
- Avoid taking with fruit juices (grapefruit, orange, apple).
- Inform your doctor about all other medications and supplements you are taking.
Missed Dose Advice
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and resume your regular dosing schedule. Do not double the dose to catch up.
Driving Precautions
Although fexofenadine is generally non-sedating, some individuals may experience drowsiness or dizziness. Exercise caution when driving or operating machinery until you know how the medicine affects you.
Lifestyle Advice
- Identify and avoid allergens that trigger your symptoms.
- Stay hydrated by drinking plenty of water.
- Consult your doctor if symptoms persist or worsen.
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Global Brand Names
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