Tempol
Generic Name
Tempol
Manufacturer
Various chemical suppliers for research purposes; no specific pharmaceutical manufacturer for human use.
Country
Various (for chemical synthesis), not a specific pharmaceutical origin for human use.
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| tempol 500 mg tablet | ৳ 0.80 | ৳ 8.00 |
Description
Overview of the medicine
Tempol is a stable nitroxide radical with antioxidant and superoxide dismutase mimetic properties. It is extensively studied in preclinical and some early clinical research for its potential in treating conditions involving oxidative stress, radiation injury, and inflammation. IMPORTANT: It is not an approved pharmaceutical drug for human clinical use.
Uses & Indications
Dosage
Adults
Not established for human clinical use. Dosage used in preclinical studies varies widely depending on species and application.
Elderly
Not established for human clinical use.
Renal_impairment
Not established for human clinical use.
How to Take
Not established for human clinical use. In research, it is administered via various routes (e.g., oral, intravenous, intraperitoneal) depending on the study model.
Mechanism of Action
Tempol acts as a scavenger of reactive oxygen species (ROS), particularly superoxide, thereby reducing oxidative stress. It can also modulate cellular redox state and may have anti-inflammatory effects.
Pharmacokinetics
Onset
Not established for human clinical use.
Excretion
Excretion routes in humans are not fully characterized for clinical use.
Half life
Variable in animal studies, not established for human clinical use.
Absorption
Pharmacokinetic data in humans is limited and not well-established for clinical use. Studies in animals show variable absorption depending on administration route.
Metabolism
Metabolic pathways in humans are not fully characterized for clinical use.
Side Effects
Contraindications
- Not established for human clinical use. Potential unknown risks.
Drug Interactions
Other Antioxidants
Potential for synergistic or antagonistic redox interactions, not clinically established.
Redox-active compounds
Potential for altered efficacy or toxicity due to interaction with cellular redox systems, not clinically established.
Storage
Store in a cool, dry place (e.g., 2-8°C or room temperature depending on supplier), protected from light and moisture, in a tightly sealed container. Keep away from strong oxidizing agents.
Overdose
Overdose management not established for human clinical use. If accidental exposure occurs, treat symptomatically and seek medical advice.
Pregnancy & Lactation
Safety not established in pregnancy or lactation for human use. Not recommended.
Side Effects
Contraindications
- Not established for human clinical use. Potential unknown risks.
Drug Interactions
Other Antioxidants
Potential for synergistic or antagonistic redox interactions, not clinically established.
Redox-active compounds
Potential for altered efficacy or toxicity due to interaction with cellular redox systems, not clinically established.
Storage
Store in a cool, dry place (e.g., 2-8°C or room temperature depending on supplier), protected from light and moisture, in a tightly sealed container. Keep away from strong oxidizing agents.
Overdose
Overdose management not established for human clinical use. If accidental exposure occurs, treat symptomatically and seek medical advice.
Pregnancy & Lactation
Safety not established in pregnancy or lactation for human use. Not recommended.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
Typically 2-5 years when stored properly, as specified by the chemical supplier.
Availability
Primarily available as a research chemical from scientific suppliers, not in pharmacies for clinical use.
Approval Status
Not approved for human clinical use by any major regulatory body (e.g., FDA, DGDA). Primarily a research chemical.
Patent Status
Patents may exist for specific research applications, but not for a generalized pharmaceutical product for human use.
Clinical Trials
Numerous preclinical studies and some early-phase (Phase I/II) clinical trials are ongoing for various investigational applications (e.g., radiation protectant, neuroprotectant), but no completed trials leading to drug approval.
Lab Monitoring
- Not established for human clinical use. In research, various biomarkers of oxidative stress may be monitored.
Doctor Notes
- Remind patients that Tempol is a research chemical and not an approved medication for human use.
- Discourage self-administration of this compound.
- Report any accidental exposure or misuse to toxicology centers.
Patient Guidelines
- Do not use for self-medication.
- This compound is for research purposes only.
- Consult a healthcare professional for any health concerns.
Missed Dose Advice
Not applicable, not an approved drug.
Driving Precautions
Not applicable, not for human clinical use. No known effects on driving.
Lifestyle Advice
- Not applicable, not for human consumption.
- Maintain a healthy lifestyle generally.
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Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.
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