Timozin
Generic Name
Timozin 5 mg Injection
Manufacturer
MediCorp Pharma Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| timozin 5 mg injection | ৳ 35.00 | N/A |
Description
Overview of the medicine
Timozin 5 mg Injection contains a beta-adrenergic blocker indicated for the management of various cardiovascular conditions such as hypertension and arrhythmias. It acts by blocking beta-receptors in the heart and blood vessels.
Uses & Indications
Dosage
Adults
Initial dose 5 mg IV, administered slowly over 5-10 minutes. May be repeated after 2-4 hours if necessary, up to a maximum daily dose of 20 mg.
Elderly
Dose adjustments may be required, starting with a lower dose and monitoring closely due to potential age-related organ impairment.
Renal_impairment
No specific dose adjustment for mild to moderate renal impairment. Use with caution in severe renal impairment, monitor for adverse effects.
How to Take
Administer intravenously slowly over 5-10 minutes by a healthcare professional. Do not administer intramuscularly or subcutaneously.
Mechanism of Action
Timozin works by competitively blocking beta1 and beta2 adrenergic receptors. This results in decreased heart rate, reduced myocardial contractility, and lower blood pressure, thereby managing conditions like hypertension and cardiac arrhythmias.
Pharmacokinetics
Onset
Within minutes (IV)
Excretion
Excreted mainly via urine, both as unchanged drug and metabolites.
Half life
Approximately 4-6 hours
Absorption
Rapidly and completely absorbed following intravenous administration.
Metabolism
Primarily hepatic metabolism
Side Effects
Contraindications
- •Bronchial asthma or severe COPD
- •Sinus bradycardia (heart rate < 45-50 bpm)
- •Second or third-degree atrioventricular block
- •Cardiogenic shock
- •Decompensated heart failure
Drug Interactions
NSAIDs
May reduce antihypertensive effect.
Digitalis Glycosides
Increased risk of bradycardia and AV block.
Calcium Channel Blockers (e.g., Verapamil, Diltiazem)
Increased risk of bradycardia and hypotension.
Storage
Store below 30°C. Protect from light. Do not freeze.
Overdose
Symptoms include severe bradycardia, hypotension, bronchospasm, and acute cardiac failure. Management involves supportive measures, atropine for bradycardia, vasopressors for hypotension, and glucagon for refractory cases.
Pregnancy & Lactation
Use during pregnancy only if the potential benefit justifies the potential risk to the fetus. Beta-blockers can cross the placenta and may cause bradycardia and hypoglycemia in the neonate. Excreted in breast milk; use with caution.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
24 months from the date of manufacture
Availability
Hospitals, Clinics, Retail Pharmacies
Approval Status
Approved by regulatory authorities (e.g., DGDA)
Patent Status
Patent Expired (Generic available)
WHO Essential Medicine
YesAlternative Medicines in Bangladesh
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Global Brand Names
International brand names for this medicine
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