Torped
Generic Name
Cefoperazone
Manufacturer
XYZ Pharmaceuticals Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| torped 500 mg injection | ৳ 75.50 | N/A |
Description
Overview of the medicine
Torped 500 mg injection contains Cefoperazone, a third-generation cephalosporin antibiotic, used to treat various bacterial infections.
Uses & Indications
Dosage
Adults
Typical dose is 1-2 grams daily, given in divided doses every 12 hours intravenously (IV) or intramuscularly (IM). In severe infections, doses up to 4 grams daily may be used.
Elderly
Standard adult dosage, but dose adjustment may be necessary based on renal function.
Renal_impairment
Dosage adjustment is required for patients with significant renal impairment.
How to Take
This injection is administered by a healthcare professional intravenously (IV) or intramuscularly (IM). It should not be self-administered.
Mechanism of Action
Cefoperazone inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs), leading to bacterial cell lysis and death.
Pharmacokinetics
Onset
Rapid onset of action after administration.
Excretion
Primarily excreted via bile and urine.
Half life
Approximately 1.5-2 hours.
Absorption
Rapidly and completely absorbed after intravenous (IV) or intramuscular (IM) administration.
Metabolism
Minimally metabolized in the liver; largely excreted unchanged.
Side Effects
Contraindications
- Hypersensitivity to cefoperazone, other cephalosporins, or penicillins.
- Known allergy to any component of the drug.
Drug Interactions
Warfarin
May increase the risk of bleeding.
Aminoglycosides
May increase the risk of nephrotoxicity (kidney toxicity).
Storage
Store below 25°C in a dry place, protected from light. Keep out of reach of children.
Overdose
In case of overdose, symptomatic and supportive treatment should be given. Hemodialysis may be helpful.
Pregnancy & Lactation
Pregnancy Category B. Should be used during pregnancy only if clearly needed. Caution is advised during lactation; consult a doctor.
Side Effects
Contraindications
- Hypersensitivity to cefoperazone, other cephalosporins, or penicillins.
- Known allergy to any component of the drug.
Drug Interactions
Warfarin
May increase the risk of bleeding.
Aminoglycosides
May increase the risk of nephrotoxicity (kidney toxicity).
Storage
Store below 25°C in a dry place, protected from light. Keep out of reach of children.
Overdose
In case of overdose, symptomatic and supportive treatment should be given. Hemodialysis may be helpful.
Pregnancy & Lactation
Pregnancy Category B. Should be used during pregnancy only if clearly needed. Caution is advised during lactation; consult a doctor.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
Usually 2 years from the date of manufacture when stored correctly.
Availability
Hospitals, pharmacies
Approval Status
Approved by regulatory authorities
Patent Status
Generic available
WHO Essential Medicine
YesClinical Trials
Numerous clinical trials have been conducted over the years establishing the efficacy and safety of Cefoperazone for various bacterial infections.
Lab Monitoring
- Renal function tests (e.g., serum creatinine, BUN)
- Hepatic function tests (e.g., ALT, AST)
- Complete Blood Count (CBC) if prolonged therapy
Doctor Notes
- Monitor renal and hepatic function, especially during prolonged therapy.
- Be aware of potential cross-allergenicity with other beta-lactam antibiotics.
- Consider combination therapy with beta-lactamase inhibitors (e.g., sulbactam) for extended spectrum activity, if appropriate.
Patient Guidelines
- Complete the full course of antibiotic treatment as prescribed by your doctor, even if you feel better.
- Report any unusual side effects or allergic reactions to your doctor immediately.
- Inform your doctor about all other medications you are taking to avoid potential drug interactions.
Missed Dose Advice
If a dose is missed, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and resume your regular dosing schedule. Do not double doses.
Driving Precautions
Generally, cefoperazone does not impair the ability to drive or operate machinery. However, if you experience dizziness or other adverse effects, avoid such activities.
Lifestyle Advice
- Stay well-hydrated during treatment.
- Maintain good hygiene to prevent further infections.
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Global Brand Names
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