Tydin
Generic Name
Paracetamol (Acetaminophen)
Manufacturer
Example Pharma Ltd.
Country
Bangladesh
Loading images...
Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| tydin 125 mg pediatric drop | ৳ 50.00 | N/A |
Description
Overview of the medicine
Tydin 125 mg Pediatric Drop is used for the symptomatic relief of mild to moderate pain and fever in infants and young children. It contains paracetamol (acetaminophen), a commonly used analgesic and antipyretic.
Uses & Indications
Dosage
Adults
Not for adult use (this is a pediatric drop).
Elderly
Not for elderly use (this is a pediatric drop).
Infants_children
10-15 mg/kg body weight per dose, every 4-6 hours as needed. Do not exceed 5 doses in 24 hours. Max daily dose: 60 mg/kg or 2.6 g, whichever is less. For infants 1-3 months: 10-15 mg/kg per dose, max 2 doses in 24 hours.
Renal_impairment
Dosage adjustment may be necessary in severe renal impairment (CrCl <10 mL/min). Consult a doctor.
How to Take
Administer orally. Use the provided dropper for accurate dosing. Shake the bottle well before use. Can be given with or without food.
Mechanism of Action
Paracetamol's exact mechanism is not fully understood but is believed to involve inhibition of prostaglandin synthesis in the central nervous system (CNS). It has weak anti-inflammatory effects.
Pharmacokinetics
Onset
Within 30-60 minutes.
Excretion
Mainly excreted in the urine as glucuronide and sulfate conjugates, with a small amount of unmetabolized paracetamol.
Half life
1.5-3 hours in adults; slightly longer in neonates and shorter in children.
Absorption
Rapidly and almost completely absorbed from the gastrointestinal tract.
Metabolism
Primarily metabolized in the liver via glucuronidation and sulfation, to a lesser extent by cytochrome P450 to a highly reactive intermediate (NAPQI), which is detoxified by glutathione.
Side Effects
Contraindications
- Hypersensitivity to paracetamol or any component of the formulation.
- Severe hepatic impairment or active liver disease.
Drug Interactions
Alcohol
Increases risk of hepatotoxicity.
Warfarin
May increase anticoagulant effect (risk of bleeding) with prolonged regular use.
Cholestyramine
Reduces paracetamol absorption if given within one hour.
Phenytoin, Phenobarbital, Carbamazepine
May increase paracetamol metabolism, potentially reducing efficacy and increasing hepatotoxicity.
Storage
Store below 30°C in a dry place, protected from light. Do not freeze. Keep away from direct sunlight.
Overdose
Symptoms include nausea, vomiting, abdominal pain, pallor, and anorexia. Severe overdose can lead to hepatotoxicity (liver damage), which may be delayed for 24-48 hours. Management involves gastric lavage, activated charcoal, and administration of N-acetylcysteine (NAC) as an antidote.
Pregnancy & Lactation
Considered safe for use during pregnancy and lactation when used at recommended doses, as it is widely used and well-tolerated. Always consult a healthcare professional.
Side Effects
Contraindications
- Hypersensitivity to paracetamol or any component of the formulation.
- Severe hepatic impairment or active liver disease.
Drug Interactions
Alcohol
Increases risk of hepatotoxicity.
Warfarin
May increase anticoagulant effect (risk of bleeding) with prolonged regular use.
Cholestyramine
Reduces paracetamol absorption if given within one hour.
Phenytoin, Phenobarbital, Carbamazepine
May increase paracetamol metabolism, potentially reducing efficacy and increasing hepatotoxicity.
Storage
Store below 30°C in a dry place, protected from light. Do not freeze. Keep away from direct sunlight.
Overdose
Symptoms include nausea, vomiting, abdominal pain, pallor, and anorexia. Severe overdose can lead to hepatotoxicity (liver damage), which may be delayed for 24-48 hours. Management involves gastric lavage, activated charcoal, and administration of N-acetylcysteine (NAC) as an antidote.
Pregnancy & Lactation
Considered safe for use during pregnancy and lactation when used at recommended doses, as it is widely used and well-tolerated. Always consult a healthcare professional.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
3 years from manufacturing date
Availability
Pharmacies, supermarkets, drug stores
Approval Status
Approved by health authorities worldwide (e.g., FDA, DGDA)
Patent Status
Generic (Patent expired for Paracetamol)
WHO Essential Medicine
YesClinical Trials
Extensively studied and widely used for decades. Numerous clinical trials confirm efficacy and safety in pediatric populations for pain and fever.
Lab Monitoring
- Liver function tests (in cases of overdose or prolonged high-dose therapy).
- Renal function tests (in patients with pre-existing renal impairment).
Doctor Notes
- Counsel parents on proper dosing using the provided dropper to avoid accidental overdose.
- Emphasize consulting a physician if symptoms worsen or new symptoms appear.
Patient Guidelines
- Always use the provided dropper for accurate measurement.
- Do not exceed the recommended dose or duration of treatment.
- Consult a doctor if fever persists for more than 3 days or pain for more than 5 days.
- Keep out of reach of children.
Missed Dose Advice
If a dose is missed, administer it as soon as remembered. If it is almost time for the next dose, skip the missed dose and continue with the regular schedule. Do not double the dose.
Driving Precautions
Not applicable for pediatric drops. Paracetamol generally does not impair ability to drive or operate machinery.
Lifestyle Advice
- Ensure adequate fluid intake, especially during fever.
- Dress lightly and avoid overheating during fever.
- Encourage rest.
Alternative Medicines in Bangladesh
Similar medicines available in the market
Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.
Other Medicines in Tydin Brand
Other medicines available under the same brand name
