Vastigro
Generic Name
Vastigro 45 mg capsule
Manufacturer
MediCorp Global
Country
USA
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| vastigro 45 mg capsule | ৳ 40.00 | ৳ 400.00 |
Description
Overview of the medicine
Vastigro 45 mg capsule is a novel growth factor stimulant indicated for conditions requiring enhanced cellular proliferation and tissue regeneration. It works by modulating specific receptor pathways.
Uses & Indications
Dosage
Adults
One 45 mg capsule orally once daily, preferably with food.
Elderly
No specific dosage adjustment required, but monitor for adverse effects.
Renal_impairment
Reduce dose to 25 mg once daily for severe impairment; consult physician.
How to Take
Take the capsule orally with a glass of water, with or without food as advised by the physician. Do not crush or chew.
Mechanism of Action
Vastigro acts as an agonist on growth factor receptors (GFRs), leading to activation of intracellular signaling cascades (e.g., MAPK/ERK, PI3K/Akt pathways) that promote cell growth, differentiation, and survival.
Pharmacokinetics
Onset
Clinical effects typically observed within 2-4 weeks of initiation of therapy.
Excretion
Excreted predominantly via renal route, with minor fecal excretion.
Half life
Approximately 8-12 hours.
Absorption
Rapidly absorbed from the gastrointestinal tract, with peak plasma concentrations reached within 2-4 hours.
Metabolism
Primarily metabolized in the liver via CYP3A4 pathway and also through peptide hydrolysis.
Side Effects
Contraindications
- Hypersensitivity to Vastigro or any excipients
- Active malignancy
- Uncontrolled hypertension
Drug Interactions
Anticoagulants
Potential for increased bleeding risk; monitor INR.
Immunosuppressants
May alter Vastigro's efficacy; close monitoring required.
Storage
Store below 30°C in a dry place, away from direct sunlight and moisture. Keep out of reach of children.
Overdose
In case of overdose, seek immediate medical attention. Symptomatic and supportive treatment should be initiated. Hemodialysis is not expected to be effective.
Pregnancy & Lactation
Use in pregnancy only if potential benefit justifies the potential risk to the fetus. Not recommended during breastfeeding due to unknown excretion into breast milk.
Side Effects
Contraindications
- Hypersensitivity to Vastigro or any excipients
- Active malignancy
- Uncontrolled hypertension
Drug Interactions
Anticoagulants
Potential for increased bleeding risk; monitor INR.
Immunosuppressants
May alter Vastigro's efficacy; close monitoring required.
Storage
Store below 30°C in a dry place, away from direct sunlight and moisture. Keep out of reach of children.
Overdose
In case of overdose, seek immediate medical attention. Symptomatic and supportive treatment should be initiated. Hemodialysis is not expected to be effective.
Pregnancy & Lactation
Use in pregnancy only if potential benefit justifies the potential risk to the fetus. Not recommended during breastfeeding due to unknown excretion into breast milk.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
24 months from manufacturing date.
Availability
Specialty pharmacies, Hospital pharmacies
Approval Status
Under clinical review
Patent Status
Patent pending
Clinical Trials
Phase III trials demonstrated significant improvement in wound healing rates and reduction in recovery time. Ongoing studies are evaluating long-term safety and efficacy.
Lab Monitoring
- Complete Blood Count (CBC)
- Renal function tests
- Liver function tests
- Coagulation parameters
Doctor Notes
- Emphasize patient education on potential side effects, especially thromboembolic events.
- Regular follow-up for monitoring treatment response and adverse effects is crucial.
- Assess for underlying malignancies before starting therapy.
Patient Guidelines
- Take consistently at the same time each day.
- Report any unusual bleeding or swelling immediately.
- Do not stop taking the medicine without consulting your doctor.
- Avoid self-medication.
Missed Dose Advice
If a dose is missed, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and resume your regular dosing schedule. Do not double the dose.
Driving Precautions
May cause dizziness or fatigue. Exercise caution while driving or operating heavy machinery until you know how Vastigro affects you.
Lifestyle Advice
- Maintain a balanced diet.
- Engage in moderate exercise.
- Avoid smoking and excessive alcohol consumption.
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