Vifas
Generic Name
Fexofenadine Hydrochloride
Manufacturer
Incepta Pharmaceuticals Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| vifas 30 mg suspension | ৳ 55.00 | N/A |
Description
Overview of the medicine
Vifas 30 mg Suspension contains Fexofenadine Hydrochloride, a non-sedating antihistamine used for symptomatic relief of seasonal allergic rhinitis and chronic idiopathic urticaria.
Uses & Indications
Dosage
Adults
60 mg (10 ml) twice daily or 120-180 mg once daily (for tablets, consult doctor for suspension dosage).
Elderly
No dose adjustment usually required unless renal impairment. If renal impairment, initial dose 30 mg (5 ml) once daily.
Renal_impairment
Initial dose 30 mg (5 ml) once daily.
How to Take
Oral suspension. Shake well before use. Can be taken with or without food. Avoid taking with fruit juice (e.g., grapefruit, orange, apple juice) as it may reduce bioavailability.
Mechanism of Action
Fexofenadine is a selective peripheral H1-receptor antagonist. It blocks the histamine H1 receptors, thereby preventing the effects of histamine which include itching, sneezing, rhinorrhea, and watery eyes.
Pharmacokinetics
Onset
Within 1 hour.
Excretion
Primarily excreted unchanged in feces (80%) and urine (11%).
Half life
Approximately 11-15 hours.
Absorption
Rapidly absorbed after oral administration. Peak plasma concentrations are reached in 1-3 hours.
Metabolism
Undergoes negligible metabolism (about 5%).
Side Effects
Contraindications
- Hypersensitivity to Fexofenadine or any component of the formulation.
- Not recommended for children under 6 months.
Drug Interactions
Erythromycin/Ketoconazole
May increase Fexofenadine plasma concentrations.
Antacids (containing aluminum and magnesium)
May decrease Fexofenadine absorption. Separate administration by at least 2 hours.
Storage
Store below 30°C in a dry place, away from light. Do not freeze. Keep out of reach of children.
Overdose
Symptoms may include dizziness, drowsiness, and dry mouth. Management is symptomatic and supportive; no specific antidote.
Pregnancy & Lactation
Pregnancy Category C. Use only if potential benefit justifies potential risk to the fetus. Excreted in breast milk, use with caution in nursing mothers.
Side Effects
Contraindications
- Hypersensitivity to Fexofenadine or any component of the formulation.
- Not recommended for children under 6 months.
Drug Interactions
Erythromycin/Ketoconazole
May increase Fexofenadine plasma concentrations.
Antacids (containing aluminum and magnesium)
May decrease Fexofenadine absorption. Separate administration by at least 2 hours.
Storage
Store below 30°C in a dry place, away from light. Do not freeze. Keep out of reach of children.
Overdose
Symptoms may include dizziness, drowsiness, and dry mouth. Management is symptomatic and supportive; no specific antidote.
Pregnancy & Lactation
Pregnancy Category C. Use only if potential benefit justifies potential risk to the fetus. Excreted in breast milk, use with caution in nursing mothers.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
Typically 2-3 years from manufacturing date when stored properly.
Availability
Pharmacies, hospitals
Approval Status
Approved by regulatory bodies (e.g., FDA, DGDA)
Patent Status
Generic available
WHO Essential Medicine
YesClinical Trials
Extensive clinical trials have established Fexofenadine's efficacy and safety for allergic rhinitis and urticaria across various age groups.
Lab Monitoring
- No specific lab monitoring required for routine use.
Doctor Notes
- Advise patients to use the provided measuring device for accurate dosing.
- Counsel parents on proper administration for pediatric patients.
Patient Guidelines
- Do not exceed the recommended dose.
- Avoid taking with fruit juices.
- Consult a doctor if symptoms do not improve or worsen.
Missed Dose Advice
Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose.
Driving Precautions
Generally non-sedating, but individual responses vary. Patients should assess their ability to drive or operate machinery before engaging in such activities.
Lifestyle Advice
- Avoid known allergens.
- Maintain good hygiene to reduce exposure to allergens.
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Global Brand Names
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