Virzith
Generic Name
Azithromycin
Manufacturer
Local Pharmaceutical Company
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| virzith 500 mg tablet | ৳ 30.00 | N/A |
| virzith 200 mg suspension | ৳ 100.00 | N/A |
Description
Overview of the medicine
Virzith contains Azithromycin, a macrolide antibiotic used to treat various bacterial infections, including respiratory tract infections, skin and soft tissue infections, and sexually transmitted infections.
Uses & Indications
Dosage
Adults
For most infections: 500 mg once daily for 3 days OR 500 mg as a single dose on Day 1, then 250 mg once daily on Days 2-5.
Elderly
No dosage adjustment is required for elderly patients with normal renal and hepatic function.
Renal_impairment
No dosage adjustment is necessary for mild to moderate renal impairment. Use with caution in severe renal impairment (CrCl <10 mL/min).
How to Take
Take with or without food. For better absorption and to minimize gastrointestinal upset, it can be taken with food. Always complete the full course as prescribed by your doctor.
Mechanism of Action
Azithromycin binds to the 50S ribosomal subunit of susceptible microorganisms and, thus, inhibits protein synthesis. This results in the inhibition of the bacteria's growth and reproduction.
Pharmacokinetics
Onset
Onset of action within 2-3 hours.
Excretion
Primarily excreted unchanged in bile; a small amount is excreted in urine.
Half life
Terminal half-life is 2-4 days.
Absorption
Rapidly absorbed from the gastrointestinal tract; bioavailability is approximately 37%.
Metabolism
Mostly metabolized in the liver.
Side Effects
Contraindications
- •Hypersensitivity to azithromycin, erythromycin, any macrolide or ketolide antibiotic, or any component of the formulation.
- •History of cholestatic jaundice/hepatic dysfunction associated with prior azithromycin use.
Drug Interactions
0
Antacids containing aluminum or magnesium: Reduce peak serum levels.
1
Warfarin: May increase the anticoagulant effect.
2
Nelfinavir: Increased azithromycin serum concentrations.
Storage
Store in a cool, dry place below 30°C, protected from light and moisture. Keep out of reach of children.
Overdose
Symptoms of overdose include severe nausea, vomiting, diarrhea, and reversible hearing loss. Management involves gastric lavage and general supportive measures as clinically indicated.
Pregnancy & Lactation
Pregnancy Category B. Use only if clearly needed. Excreted in breast milk; use with caution in nursing mothers.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
24-36 months from manufacturing date
Availability
Available in pharmacies and hospitals
Approval Status
Approved (DGDA)
Patent Status
Generic available
WHO Essential Medicine
YesAlternative Medicines in Bangladesh
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Global Brand Names
International brand names for this medicine
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