Visral
Generic Name
visral-5-mg-injection
Manufacturer
Incepta Pharmaceuticals Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| visral 5 mg injection | ৳ 30.00 | N/A |
Description
Overview of the medicine
Visral 5 mg Injection contains Hyoscine Butylbromide, an antispasmodic agent used to relieve painful cramps and spasms of the smooth muscles of the gastrointestinal, biliary, and genitourinary tracts.
Uses & Indications
Dosage
Adults
Typically 20 mg intramuscularly or intravenously, repeated every 30 minutes if necessary, but not to exceed 100 mg per day.
Elderly
Similar to adult dosage, but caution should be exercised in patients with underlying conditions.
Renal_impairment
No specific dose adjustment required, but caution is advised due to renal excretion.
How to Take
Administered by healthcare professionals via intramuscular (IM) or slow intravenous (IV) injection.
Mechanism of Action
Hyoscine Butylbromide is an anticholinergic agent that specifically acts as a muscarinic receptor antagonist. It blocks the action of acetylcholine at muscarinic receptors in the smooth muscles of the gastrointestinal, biliary, and genitourinary tracts, leading to relaxation of these muscles and relief of spasms.
Pharmacokinetics
Onset
Rapid, within minutes after IV administration.
Excretion
Mainly excreted via renal and biliary routes, largely as unchanged drug and metabolites.
Half life
Short plasma half-life, typically a few hours.
Absorption
Poorly absorbed from the gastrointestinal tract; primarily administered parenterally for systemic effect. After IV administration, it is rapidly distributed.
Metabolism
Partially metabolized in the liver.
Side Effects
Contraindications
- Glaucoma (narrow-angle)
- Prostatic hypertrophy with urinary retention
- Mechanical stenosis of the gastrointestinal tract
- Paralytic or obstructive ileus
- Tachycardia
- Myasthenia gravis
- Megacolon
Drug Interactions
Beta-agonists
May increase heart rate.
Antihistamines
May increase anticholinergic effects.
Phenothiazines
May increase anticholinergic effects.
Tricyclic antidepressants
May potentiate the anticholinergic effects.
Storage
Store below 30°C, protected from light. Do not freeze.
Overdose
Symptoms include anticholinergic effects like dry mouth, blurred vision, tachycardia, and urinary retention. Treatment is symptomatic and supportive; physostigmine may be used as an antidote in severe cases.
Pregnancy & Lactation
Use with caution during pregnancy, especially in the first trimester. Limited data on excretion into breast milk; use only if clearly needed after consulting a doctor.
Side Effects
Contraindications
- Glaucoma (narrow-angle)
- Prostatic hypertrophy with urinary retention
- Mechanical stenosis of the gastrointestinal tract
- Paralytic or obstructive ileus
- Tachycardia
- Myasthenia gravis
- Megacolon
Drug Interactions
Beta-agonists
May increase heart rate.
Antihistamines
May increase anticholinergic effects.
Phenothiazines
May increase anticholinergic effects.
Tricyclic antidepressants
May potentiate the anticholinergic effects.
Storage
Store below 30°C, protected from light. Do not freeze.
Overdose
Symptoms include anticholinergic effects like dry mouth, blurred vision, tachycardia, and urinary retention. Treatment is symptomatic and supportive; physostigmine may be used as an antidote in severe cases.
Pregnancy & Lactation
Use with caution during pregnancy, especially in the first trimester. Limited data on excretion into breast milk; use only if clearly needed after consulting a doctor.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
Typically 2-3 years, refer to specific product packaging.
Availability
Pharmacies, hospitals, clinics
Approval Status
Approved by regulatory bodies (e.g., DGDA)
Patent Status
Off-patent
WHO Essential Medicine
YesClinical Trials
Numerous clinical trials have established its efficacy and safety for various spasmodic conditions. Ongoing research explores new applications or formulations.
Lab Monitoring
- Monitor heart rate and blood pressure in susceptible patients.
- Monitor for signs of urinary retention.
Doctor Notes
- Ensure proper diagnosis before administration.
- Monitor for signs of acute glaucoma or urinary retention, especially in elderly patients.
- Not for use in children under 6 years without specific medical advice.
Patient Guidelines
- Report any severe side effects immediately.
- Inform your doctor about all other medications you are taking.
- Do not self-administer this injection.
Missed Dose Advice
As this is an injection administered by a healthcare professional, a missed dose is unlikely in a clinical setting. If an appointment is missed, contact your doctor immediately.
Driving Precautions
May cause blurred vision or dizziness; patients should avoid driving or operating machinery until vision and coordination are clear.
Lifestyle Advice
- Maintain adequate hydration to alleviate dry mouth.
- Avoid activities requiring sharp vision if experiencing blurred vision.
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