For intravenous use only. Reconstitute the powder with sterile water for injection as per manufacturer's instructions. Administer by slow intravenous injection over 3-4 minutes or by intravenous infusion over 30-40 minutes.

Amoxicillin inhibits bacterial cell wall synthesis. Clavulanic acid is a beta-lactamase inhibitor that protects amoxicillin from degradation by beta-lactamase enzymes produced by resistant bacteria, thereby extending its antibacterial spectrum.

• •Hypersensitivity to amoxicillin, clavulanic acid, or any other penicillin antibiotic.
• •History of severe immediate hypersensitivity reaction (e.g., anaphylaxis) to another beta-lactam agent (e.g., cephalosporin, carbapenem or monobactam).
• •History of amoxicillin/clavulanate-associated jaundice or hepatic dysfunction.

Store in a cool, dry place, below 25°C-30°C. Protect from light and moisture. Do not freeze. Reconstituted solution should be used immediately or stored as per manufacturer's guidelines.

Symptoms of overdose may include gastrointestinal symptoms (nausea, vomiting, diarrhea) and disturbances in fluid and electrolyte balance. Convulsions may occur in patients with impaired renal function or those receiving high doses. Treatment is symptomatic and supportive. Hemodialysis can remove both amoxicillin and clavulanic acid from circulation.

Pregnancy Category B. Use only if clearly needed after careful risk-benefit assessment. Both amoxicillin and clavulanic acid are excreted into breast milk. Caution should be exercised when administered to a nursing mother. Monitor breastfed infants for potential adverse effects (e.g., diarrhea, fungal infections).