Axim

Axim 1.5 gm Injection should be administered intravenously (IV) or intramuscularly (IM) after reconstitution with appropriate diluents (e.g., Water for Injection). For IV administration, inject slowly over 3-5 minutes or infuse over 30-60 minutes. For IM administration, inject deep into a large muscle mass.

Cefuroxime acts by inhibiting bacterial cell wall synthesis, primarily by binding to penicillin-binding proteins (PBPs) located inside the bacterial cell wall. This binding prevents the cross-linking of peptidoglycan units, which are essential for the integrity and rigidity of the bacterial cell wall, leading to cell lysis and bacterial death.

• Hypersensitivity to cefuroxime or any other cephalosporin antibiotics
• History of severe hypersensitivity reaction to any beta-lactam antibiotic (e.g., penicillins)

Store dry powder below 30°C, protected from light and moisture. Reconstituted solution should be used immediately; if not, store in a refrigerator (2-8°C) for up to 24 hours.

Symptoms of overdose include neurological sequelae such as encephalopathy, convulsions, and coma, especially in patients with renal impairment. Treatment is symptomatic and supportive. Hemodialysis can aid in the removal of cefuroxime from the body.

Pregnancy Category B. Use with caution during pregnancy if clearly needed. Excreted in breast milk in small amounts; generally considered safe, but monitor infant for potential side effects (e.g., diarrhea, candidiasis).

• Hypersensitivity to cefuroxime or any other cephalosporin antibiotics
• History of severe hypersensitivity reaction to any beta-lactam antibiotic (e.g., penicillins)

Store dry powder below 30°C, protected from light and moisture. Reconstituted solution should be used immediately; if not, store in a refrigerator (2-8°C) for up to 24 hours.

Symptoms of overdose include neurological sequelae such as encephalopathy, convulsions, and coma, especially in patients with renal impairment. Treatment is symptomatic and supportive. Hemodialysis can aid in the removal of cefuroxime from the body.

Pregnancy Category B. Use with caution during pregnancy if clearly needed. Excreted in breast milk in small amounts; generally considered safe, but monitor infant for potential side effects (e.g., diarrhea, candidiasis).