Axodin
Generic Name
Fexofenadine Hydrochloride
Manufacturer
Square Pharmaceuticals Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| axodin 30 mg suspension | ৳ 55.00 | N/A |
Description
Overview of the medicine
Axodin suspension contains Fexofenadine, a non-drowsy antihistamine used to relieve symptoms of seasonal allergies and chronic hives.
Uses & Indications
Dosage
Adults
Not typically indicated for adults at this strength. Higher strengths are available for adult use.
Renal_impairment
For patients with impaired renal function, a starting dose of 30 mg (5 ml) once daily is recommended for children 2-11 years, and 15 mg (2.5 ml) once daily for children 6 months-2 years.
Children_2_11_years
30 mg (5 ml) orally twice daily.
Children_6_months_2_years
15 mg (2.5 ml) orally twice daily.
How to Take
Shake the bottle well before each use. Administer orally, with or without food. Use a calibrated measuring device to ensure accurate dosing.
Mechanism of Action
Fexofenadine acts as a selective peripheral H1-receptor antagonist. It blocks the action of histamine, a natural substance in the body that causes allergic symptoms.
Pharmacokinetics
Onset
Onset of action is typically within 1 hour.
Excretion
Primarily excreted unchanged, with about 80% via bile and 10% via urine.
Half life
The elimination half-life is 11 to 15 hours.
Absorption
Rapidly absorbed after oral administration. Peak plasma concentrations are reached in 1-3 hours. Bioavailability is approximately 33%.
Metabolism
Minimally metabolized; approximately 5% of the dose is metabolized in the liver.
Side Effects
Contraindications
- Hypersensitivity to fexofenadine or any component of the suspension.
Drug Interactions
Erythromycin and Ketoconazole
May increase fexofenadine plasma concentrations, although this generally does not lead to increased side effects.
Antacids containing aluminum and magnesium
May decrease the absorption of fexofenadine. Separate administration by at least 2 hours.
Storage
Store below 30°C in a dry place, away from direct sunlight. Do not freeze. Keep out of reach of children.
Overdose
Symptoms of overdose may include drowsiness, dizziness, and dry mouth. Treatment is symptomatic and supportive. Standard measures to remove unabsorbed drug should be considered.
Pregnancy & Lactation
Pregnancy Category C. Use during pregnancy only if the potential benefit justifies the potential risk to the fetus. Fexofenadine is excreted in human breast milk; use with caution in nursing mothers.
Side Effects
Contraindications
- Hypersensitivity to fexofenadine or any component of the suspension.
Drug Interactions
Erythromycin and Ketoconazole
May increase fexofenadine plasma concentrations, although this generally does not lead to increased side effects.
Antacids containing aluminum and magnesium
May decrease the absorption of fexofenadine. Separate administration by at least 2 hours.
Storage
Store below 30°C in a dry place, away from direct sunlight. Do not freeze. Keep out of reach of children.
Overdose
Symptoms of overdose may include drowsiness, dizziness, and dry mouth. Treatment is symptomatic and supportive. Standard measures to remove unabsorbed drug should be considered.
Pregnancy & Lactation
Pregnancy Category C. Use during pregnancy only if the potential benefit justifies the potential risk to the fetus. Fexofenadine is excreted in human breast milk; use with caution in nursing mothers.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
24 months from the date of manufacture.
Availability
Pharmacies, Hospitals
Approval Status
Approved
Patent Status
Generic available
Clinical Trials
Extensive clinical trials have demonstrated the efficacy and safety of fexofenadine in treating seasonal allergic rhinitis and chronic idiopathic urticaria across various age groups, including pediatric populations.
Lab Monitoring
- No routine laboratory monitoring is required for fexofenadine therapy.
Doctor Notes
- Counsel parents/guardians on proper dosing technique using the provided measuring device.
- Advise caution regarding co-administration with fruit juices and certain antacids.
- Consider renal function in pediatric patients for appropriate dose adjustment.
Patient Guidelines
- Take exactly as prescribed by your doctor.
- Shake the suspension well before each use.
- Do not take with fruit juices (grapefruit, orange, apple) as this may reduce effectiveness.
- If symptoms do not improve or worsen, consult your doctor.
Missed Dose Advice
If a dose is missed, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and resume your regular dosing schedule. Do not double the dose to catch up.
Driving Precautions
Fexofenadine is generally non-sedating, but individuals should be cautious when driving or operating machinery until they know how the medicine affects them.
Lifestyle Advice
- Avoid known allergens to help manage allergy symptoms.
- Maintain good hydration.
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Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.
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