Azmasol
Generic Name
Salbutamol
Manufacturer
Square Pharmaceuticals Ltd.
Country
Bangladesh
Loading images...
Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| azmasol 5 mg respirator solution | ৳ 120.00 | N/A |
Description
Overview of the medicine
Azmasol 5 mg Respirator Solution contains Salbutamol, a selective beta-2 adrenergic agonist. It is used for the treatment and prevention of bronchospasm in patients with reversible obstructive airway disease, such as asthma and chronic obstructive pulmonary disease (COPD).
Uses & Indications
Dosage
Adults
2.5 mg or 5 mg via nebulizer, 3-4 times daily as needed. For severe cases, higher doses may be used under medical supervision.
Elderly
Similar to adult dose, monitor for adverse effects.
Renal_impairment
No specific dosage adjustment recommended, but use with caution.
How to Take
Administer by nebulization. The solution should not be injected or swallowed. Dilution may be required as per physician's instruction.
Mechanism of Action
Salbutamol selectively stimulates beta-2 adrenergic receptors in the bronchial smooth muscle, leading to relaxation of the muscle and bronchodilation. It also inhibits the release of mediators from mast cells in the airway.
Pharmacokinetics
Onset
5-15 minutes after inhalation.
Excretion
Primarily excreted in urine as unchanged drug and its metabolite.
Half life
Approximately 2.7 to 5 hours.
Absorption
Rapidly absorbed after inhalation. Systemic bioavailability is about 10-20% for inhaled doses.
Metabolism
Partially metabolized in the liver to an inactive sulfate conjugate.
Side Effects
Contraindications
- Hypersensitivity to salbutamol or any component of the solution.
- Severe allergic reactions to other sympathomimetics.
Drug Interactions
Diuretics (e.g., Furosemide)
May potentiate hypokalemia when co-administered with salbutamol.
Beta-blockers (e.g., Propranolol)
Can inhibit the bronchodilatory effect of salbutamol and may cause severe bronchospasm.
MAO Inhibitors & Tricyclic Antidepressants
May potentiate the cardiovascular effects of salbutamol.
Storage
Store below 30°C. Protect from light and moisture. Do not freeze. Keep out of reach of children.
Overdose
Symptoms include tachycardia, tremor, headache, palpitations, and hypokalemia. Management involves symptomatic and supportive therapy, and careful monitoring of cardiac status and potassium levels.
Pregnancy & Lactation
Pregnancy Category C. Use during pregnancy only if the potential benefit justifies the potential risk to the fetus. Salbutamol may be excreted in breast milk; use with caution in nursing mothers.
Side Effects
Contraindications
- Hypersensitivity to salbutamol or any component of the solution.
- Severe allergic reactions to other sympathomimetics.
Drug Interactions
Diuretics (e.g., Furosemide)
May potentiate hypokalemia when co-administered with salbutamol.
Beta-blockers (e.g., Propranolol)
Can inhibit the bronchodilatory effect of salbutamol and may cause severe bronchospasm.
MAO Inhibitors & Tricyclic Antidepressants
May potentiate the cardiovascular effects of salbutamol.
Storage
Store below 30°C. Protect from light and moisture. Do not freeze. Keep out of reach of children.
Overdose
Symptoms include tachycardia, tremor, headache, palpitations, and hypokalemia. Management involves symptomatic and supportive therapy, and careful monitoring of cardiac status and potassium levels.
Pregnancy & Lactation
Pregnancy Category C. Use during pregnancy only if the potential benefit justifies the potential risk to the fetus. Salbutamol may be excreted in breast milk; use with caution in nursing mothers.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
24-36 months from manufacturing date, when stored appropriately.
Availability
Pharmacies, Hospitals
Approval Status
Approved by regulatory authorities
Patent Status
Expired
WHO Essential Medicine
YesClinical Trials
Extensive clinical trials have established the efficacy and safety of salbutamol in the management of asthma and COPD across various age groups. Ongoing research explores optimized delivery methods and specific patient populations.
Lab Monitoring
- Serum potassium levels (especially with high doses or concomitant diuretics)
- Pulmonary function tests (spirometry)
Doctor Notes
- Educate patients on proper nebulizer technique to ensure optimal drug delivery.
- Advise patients not to exceed prescribed doses due to potential cardiovascular adverse effects.
- Consider alternative therapies or dose adjustment if bronchodilatory response diminishes over time.
Patient Guidelines
- Use exactly as prescribed by your doctor.
- Do not exceed the recommended dose.
- Seek immediate medical attention if breathing difficulties worsen or do not improve.
Missed Dose Advice
If a dose is missed, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and resume your regular dosing schedule. Do not double the dose.
Driving Precautions
Salbutamol may cause tremor or dizziness in some patients. Patients should be advised to exercise caution when driving or operating machinery until they know how the medication affects them.
Lifestyle Advice
- Avoid known asthma triggers.
- Smoking cessation is highly recommended for patients with COPD.
- Maintain a healthy lifestyle and diet.
Alternative Medicines in Bangladesh
Similar medicines available in the market
Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.
Other Medicines in Azmasol Brand
Other medicines available under the same brand name
