Denixil
Generic Name
Denixil 1 mg Tablet
Manufacturer
PharmaCorp Bangladesh Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| denixil 1 mg tablet | ৳ 9.00 | ৳ 90.00 |
Description
Overview of the medicine
Denixil 1 mg Tablet is an anxiolytic medicine used to treat anxiety disorders and short-term insomnia. It works by affecting specific brain chemicals to produce a calming effect.
Uses & Indications
Dosage
Adults
1 mg taken orally, 2-3 times daily, or as directed by a physician.
Elderly
Initial dose of 0.5 mg, 2 times daily, adjusted as needed and tolerated.
Renal_impairment
Dosage adjustment may be necessary; consult a physician.
How to Take
Take orally with or without food. Do not crush or chew the tablet.
Mechanism of Action
Denixil enhances the effect of gamma-aminobutyric acid (GABA), a neurotransmitter that inhibits brain activity, leading to sedative, hypnotic, anxiolytic, anticonvulsant, and muscle relaxant properties.
Pharmacokinetics
Onset
15-30 minutes.
Excretion
Excreted mainly in urine as metabolites.
Half life
10-20 hours (variable).
Absorption
Rapidly absorbed after oral administration, peak plasma concentrations typically within 1-2 hours.
Metabolism
Primarily hepatic metabolism via glucuronidation.
Side Effects
Contraindications
- •Known hypersensitivity to benzodiazepines
- •Acute narrow-angle glaucoma
- •Severe respiratory insufficiency
Drug Interactions
Alcohol
Potentiates CNS depressant effects.
Opioids
Increased risk of respiratory depression and sedation.
Antifungals (e.g., Ketoconazole)
May increase Denixil levels.
Storage
Store below 30°C in a dry place, away from light. Keep out of reach of children.
Overdose
Symptoms include drowsiness, confusion, ataxia, diminished reflexes, and coma. Management is supportive, including gastric lavage and monitoring vital signs. Flumazenil may be considered in severe cases.
Pregnancy & Lactation
Use during pregnancy only if clearly needed and the potential benefits outweigh the risks. Excreted in breast milk; consult physician.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
36 months from manufacturing date.
Availability
Pharmacies, Hospitals
Approval Status
Approved by DGDA
Patent Status
Off-patent
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Global Brand Names
International brand names for this medicine
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