Take the tablet whole with a glass of water, preferably at the start of a meal to minimize potential gastrointestinal intolerance. Do not chew or crush the tablet.

Amoxicillin inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs), leading to bacterial cell lysis and death. Clavulanic Acid inactivates various beta-lactamase enzymes produced by bacteria, extending Amoxicillin's spectrum of activity to include many beta-lactamase-producing strains that would otherwise be resistant.

• •Hypersensitivity to Amoxicillin, Clavulanic Acid, any penicillin, or any other component of the formulation.
• •History of severe hypersensitivity reaction to any other beta-lactam agent (e.g., cephalosporins, carbapenems, monobactams).
• •History of cholestatic jaundice/hepatic dysfunction associated with Amoxicillin/Clavulanic Acid.

Store below 30°C in a dry place, away from direct light and moisture. Keep out of reach of children.

Symptoms of overdose may include gastrointestinal symptoms (e.g., nausea, vomiting, diarrhea) and disturbances of fluid and electrolyte balance. In isolated cases, crystalluria leading to renal failure has been observed. Management is symptomatic and supportive, focusing on fluid and electrolyte balance. Hemodialysis can be used to remove the drug from circulation.

Pregnancy Category B. Studies in animals have shown no evidence of harm to the fetus. However, use during pregnancy should be considered only if clearly needed. Both Amoxicillin and Clavulanic Acid are excreted into breast milk; therefore, caution should be exercised when administered to a nursing woman.