Gabatec
Generic Name
Gabapentin
Manufacturer
Square Pharmaceuticals Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| gabatec 150 mg capsule | ৳ 30.00 | ৳ 240.00 |
Description
Overview of the medicine
Gabapentin is an anticonvulsant medication used to treat partial seizures and neuropathic pain, such as postherpetic neuralgia.
Uses & Indications
Dosage
Adults
Initial dose typically 300 mg three times daily, adjusted based on response and tolerability, up to 1800-3600 mg/day in divided doses. Gabatec 150 mg might be used for titration or specific conditions.
Elderly
Dose adjustment may be necessary due to reduced renal function; start with lower doses.
Renal_impairment
Dose must be reduced based on creatinine clearance.
How to Take
Take orally with or without food. Swallow capsules whole with water. Do not crush, chew, or break.
Mechanism of Action
Gabapentin is thought to exert its anticonvulsant and analgesic effects by binding to the alpha-2-delta subunit of voltage-gated calcium channels in the central nervous system, reducing the release of excitatory neurotransmitters.
Pharmacokinetics
Onset
Within hours to days for anticonvulsant effect; several weeks for neuropathic pain relief.
Excretion
Excreted unchanged by the kidneys.
Half life
5 to 7 hours.
Absorption
Well absorbed from the gastrointestinal tract, but absorption is dose-dependent and saturable.
Metabolism
Not significantly metabolized in humans. Does not induce or inhibit hepatic enzyme systems.
Side Effects
Contraindications
- Hypersensitivity to gabapentin or any component of the formulation.
- Acute pancreatitis (rare, but reported).
Drug Interactions
Antacids
May decrease gabapentin bioavailability; separate administration by at least 2 hours.
Opioid analgesics (e.g., Morphine)
May increase gabapentin concentrations and enhance CNS depressant effects.
CNS depressants (e.g., Alcohol, Benzodiazepines)
May potentiate CNS depressant effects of gabapentin.
Storage
Store below 30°C in a dry place, away from light and moisture. Keep out of reach of children.
Overdose
Symptoms include dizziness, double vision, slurred speech, drowsiness, lethargy, and mild diarrhea. Management is supportive, including gastric lavage and activated charcoal if recent ingestion. Hemodialysis can be used to remove gabapentin.
Pregnancy & Lactation
Pregnancy Category C. Use only if potential benefit outweighs potential risk to the fetus. Gabapentin is excreted in breast milk; caution is advised during breastfeeding.
Side Effects
Contraindications
- Hypersensitivity to gabapentin or any component of the formulation.
- Acute pancreatitis (rare, but reported).
Drug Interactions
Antacids
May decrease gabapentin bioavailability; separate administration by at least 2 hours.
Opioid analgesics (e.g., Morphine)
May increase gabapentin concentrations and enhance CNS depressant effects.
CNS depressants (e.g., Alcohol, Benzodiazepines)
May potentiate CNS depressant effects of gabapentin.
Storage
Store below 30°C in a dry place, away from light and moisture. Keep out of reach of children.
Overdose
Symptoms include dizziness, double vision, slurred speech, drowsiness, lethargy, and mild diarrhea. Management is supportive, including gastric lavage and activated charcoal if recent ingestion. Hemodialysis can be used to remove gabapentin.
Pregnancy & Lactation
Pregnancy Category C. Use only if potential benefit outweighs potential risk to the fetus. Gabapentin is excreted in breast milk; caution is advised during breastfeeding.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
Typically 24-36 months from manufacturing date
Availability
Pharmacies, Hospitals
Approval Status
Approved (e.g., FDA, DGDA)
Patent Status
Patent expired (Generic available)
WHO Essential Medicine
YesClinical Trials
Extensive clinical trials have established gabapentin's efficacy and safety for its approved indications. Ongoing research explores its use in other neurological conditions.
Lab Monitoring
- Renal function (creatinine clearance) if impairment is suspected or in elderly patients.
- Monitor for signs of suicidal ideation or unusual behavior changes.
Doctor Notes
- Advise patients about the potential for sedation and dizziness, especially when initiating therapy.
- Caution in patients with renal impairment; adjust dose accordingly.
- Monitor for signs of suicidal ideation, especially during initial therapy or dose changes.
Patient Guidelines
- Do not stop taking gabapentin suddenly without consulting your doctor, as this may lead to withdrawal symptoms or increased seizures.
- Report any unusual mood changes, depression, or suicidal thoughts to your doctor immediately.
- Avoid driving or operating heavy machinery until you know how this medication affects you, as it can cause dizziness and drowsiness.
Missed Dose Advice
If a dose is missed, take it as soon as you remember. If it is close to the time for the next dose, skip the missed dose and resume your regular dosing schedule. Do not double the dose.
Driving Precautions
Gabapentin may cause dizziness, drowsiness, and blurred vision, which can impair your ability to drive or operate machinery. Exercise caution or avoid these activities until you know how the medication affects you.
Lifestyle Advice
- Maintain a regular sleep schedule.
- Avoid alcohol consumption while on gabapentin.
- Stay hydrated.
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Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.
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