Initer
Generic Name
Human Chorionic Gonadotropin (hCG)
Manufacturer
Reputable Pharmaceutical Co.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| initer 5000 iu injection | ৳ 2,557.71 | N/A |
Description
Overview of the medicine
Human Chorionic Gonadotropin (hCG) is a hormone produced by the placenta during pregnancy. In medicine, it is used to treat fertility problems in both men and women, and in some cases, cryptorchidism (undescended testicles) in pre-pubertal boys.
Uses & Indications
Dosage
Adults
Varies widely based on indication. E.g., for ovulation induction, 5000-10000 IU is given 1 day after last dose of menotropins. For male hypogonadism, 500-4000 IU 2-3 times/week.
Elderly
Dosage adjustments usually not required unless significant renal/hepatic impairment.
Renal_impairment
Use with caution; monitor for potential accumulation.
How to Take
Administered intramuscularly or subcutaneously after reconstitution with the provided solvent.
Mechanism of Action
hCG acts like Luteinizing Hormone (LH) and stimulates the gonads. In females, it induces ovulation and maintains the corpus luteum. In males, it stimulates testosterone production and spermatogenesis.
Pharmacokinetics
Onset
Ovulation typically occurs 36-40 hours after administration.
Excretion
Excreted via the kidneys, mainly as metabolites.
Half life
Approximately 24-36 hours.
Absorption
Rapidly absorbed after intramuscular or subcutaneous injection.
Metabolism
Primarily metabolized in the liver.
Side Effects
Contraindications
- Hypersensitivity to hCG or any component of the formulation.
- Precocious puberty, androgen-dependent tumors (e.g., prostate carcinoma, male breast carcinoma).
- Uncontrolled thyroid or adrenal dysfunction.
Drug Interactions
No significant interactions are commonly reported.
HCG generally has few significant drug interactions.
Storage
Store in a refrigerator (2-8°C). Protect from light. Do not freeze. After reconstitution, use immediately.
Overdose
Symptoms may include ovarian hyperstimulation syndrome (OHSS) in females. Management is symptomatic and supportive.
Pregnancy & Lactation
Pregnancy: Contraindicated in pregnant women (except for its natural role in pregnancy detection). Lactation: Not recommended during breastfeeding.
Side Effects
Contraindications
- Hypersensitivity to hCG or any component of the formulation.
- Precocious puberty, androgen-dependent tumors (e.g., prostate carcinoma, male breast carcinoma).
- Uncontrolled thyroid or adrenal dysfunction.
Drug Interactions
No significant interactions are commonly reported.
HCG generally has few significant drug interactions.
Storage
Store in a refrigerator (2-8°C). Protect from light. Do not freeze. After reconstitution, use immediately.
Overdose
Symptoms may include ovarian hyperstimulation syndrome (OHSS) in females. Management is symptomatic and supportive.
Pregnancy & Lactation
Pregnancy: Contraindicated in pregnant women (except for its natural role in pregnancy detection). Lactation: Not recommended during breastfeeding.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
24-36 months
Availability
Pharmacies, Hospitals
Approval Status
Approved
Patent Status
Generic available
Clinical Trials
Extensively studied for fertility treatments and other approved indications; ongoing research into new applications.
Lab Monitoring
- Ovarian ultrasound and serum estradiol levels in women undergoing fertility treatment
- Testosterone levels in men
Doctor Notes
- Monitor patients closely for signs of Ovarian Hyperstimulation Syndrome (OHSS).
- Educate patients on proper injection technique and storage.
- Provide clear instructions on dosage and timing, especially for fertility treatments.
Patient Guidelines
- Follow your doctor's instructions carefully.
- Report any unusual symptoms immediately.
- Ensure proper injection technique if self-administering.
Missed Dose Advice
Contact your doctor immediately if a dose is missed. Do not double the next dose.
Driving Precautions
No specific precautions, but if experiencing side effects like dizziness, avoid driving.
Lifestyle Advice
- Maintain a healthy diet and lifestyle during treatment.
- Avoid alcohol and smoking as they can affect fertility.
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