Lutisone
Generic Name
Lutisone 0.05% Ointment
Manufacturer
Fictional Pharma Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| lutisone 0005 ointment | ৳ 50.00 | N/A |
Description
Overview of the medicine
Lutisone 0.05% Ointment is a high-potency topical corticosteroid used for various inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses.
Uses & Indications
Dosage
Adults
Apply a thin film to the affected skin area once or twice daily. Do not exceed 2 weeks of continuous treatment.
Elderly
Same as adults, but caution with thin skin or comorbidities.
Renal_impairment
No specific dosage adjustment needed for topical application.
How to Take
For external use only. Apply a thin layer to the affected skin and rub in gently. Wash hands immediately after application.
Mechanism of Action
Lutisone, a synthetic corticosteroid, exerts its effects by binding to glucocorticoid receptors in the cytoplasm, leading to the regulation of gene expression. This results in anti-inflammatory, antipruritic, and vasoconstrictive actions.
Pharmacokinetics
Onset
Within hours for symptomatic relief.
Excretion
Excreted mainly in urine and feces, predominantly as metabolites, if systemically absorbed.
Half life
Not well-defined for topical application due to minimal systemic absorption; systemic corticosteroids have half-lives ranging from hours to days.
Absorption
Minimal systemic absorption through intact skin; increased with occlusion, inflammation, or prolonged use.
Metabolism
Primarily in the liver if systemically absorbed.
Side Effects
Contraindications
- Hypersensitivity to Lutisone or any component of the ointment.
- Bacterial, fungal, or viral infections of the skin (unless co-administered with appropriate anti-infective therapy).
- Acne, rosacea, perioral dermatitis.
Drug Interactions
Drug 1
No significant drug interactions reported for topical application due to minimal systemic absorption.
Drug 2
Potentially increased systemic absorption if used with other drugs affecting skin barrier, though clinical significance is low.
Storage
Store below 30°C. Do not freeze. Keep out of reach of children.
Overdose
Acute overdose is unlikely with topical use. Chronic overdose or misuse may lead to systemic effects like Cushing's syndrome or local side effects like skin atrophy. Treatment is symptomatic and supportive.
Pregnancy & Lactation
Use only if the potential benefit justifies the potential risk to the fetus/infant. Consult a doctor.
Side Effects
Contraindications
- Hypersensitivity to Lutisone or any component of the ointment.
- Bacterial, fungal, or viral infections of the skin (unless co-administered with appropriate anti-infective therapy).
- Acne, rosacea, perioral dermatitis.
Drug Interactions
Drug 1
No significant drug interactions reported for topical application due to minimal systemic absorption.
Drug 2
Potentially increased systemic absorption if used with other drugs affecting skin barrier, though clinical significance is low.
Storage
Store below 30°C. Do not freeze. Keep out of reach of children.
Overdose
Acute overdose is unlikely with topical use. Chronic overdose or misuse may lead to systemic effects like Cushing's syndrome or local side effects like skin atrophy. Treatment is symptomatic and supportive.
Pregnancy & Lactation
Use only if the potential benefit justifies the potential risk to the fetus/infant. Consult a doctor.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
24 months
Availability
Pharmacies, hospitals
Approval Status
Approved by local regulatory authority
Patent Status
Generic available
Clinical Trials
Details on phase III trials showing efficacy in severe dermatoses are available upon request.
Lab Monitoring
- No routine lab monitoring required for typical topical use.
- Consider adrenal function tests if extensive or prolonged use is suspected of causing systemic absorption.
Doctor Notes
- Emphasize short-term use for high-potency topical steroids.
- Monitor for signs of local skin reactions and systemic absorption, especially in pediatric patients.
Patient Guidelines
- Use exactly as prescribed by your doctor.
- Do not cover the treated area with bandages or airtight dressings unless instructed by a doctor.
- Avoid contact with eyes, mouth, and other mucous membranes.
Missed Dose Advice
Apply the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not apply extra to make up for a missed dose.
Driving Precautions
Does not affect ability to drive or operate machinery.
Lifestyle Advice
- Maintain good skin hygiene.
- Avoid known irritants or allergens.
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Global Brand Names
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