Maprocin
Generic Name
Azithromycin
Manufacturer
Square Pharmaceuticals Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| maprocin 250 mg suspension | ৳ 100.00 | N/A |
Description
Overview of the medicine
Maprocin suspension contains Azithromycin, a macrolide antibiotic used to treat a wide range of bacterial infections including respiratory tract infections, skin and soft tissue infections, and sexually transmitted diseases.
Uses & Indications
Dosage
Adults
Usually 500 mg once on the first day, then 250 mg once daily for 4 days, or as directed.
Elderly
No dosage adjustment needed unless severe renal or hepatic impairment is present.
Renal_impairment
No dosage adjustment necessary for mild to moderate renal impairment; use with caution in severe impairment.
How to Take
For oral use. Shake the bottle well before use. Use the provided measuring device to ensure accurate dosing. Can be taken with or without food.
Mechanism of Action
Azithromycin inhibits bacterial protein synthesis by binding to the 50S ribosomal subunit, thereby interfering with the translation of mRNA and ultimately inhibiting bacterial growth.
Pharmacokinetics
Onset
2-3 hours
Excretion
Primarily excreted unchanged in bile, with a small amount excreted in urine.
Half life
Approximately 68 hours (prolonged)
Absorption
Rapidly absorbed from the gastrointestinal tract; absorption may be slightly altered by food.
Metabolism
Partially metabolized in the liver.
Side Effects
Contraindications
- Hypersensitivity to azithromycin or any other macrolide antibiotic
- History of cholestatic jaundice/hepatic dysfunction associated with prior azithromycin use
Drug Interactions
Digoxin
May increase serum digoxin levels.
Antacids
May decrease the absorption of azithromycin; administer 2-4 hours apart.
Warfarin
May increase the risk of bleeding.
Nelfinavir
May increase azithromycin concentrations.
Storage
Store dry powder below 30°C, protected from light. Store reconstituted suspension at room temperature or refrigerated (as directed) and discard after the specified period.
Overdose
Symptoms of overdose may include severe nausea, vomiting, diarrhea, and abdominal pain. Symptomatic and supportive treatment should be initiated.
Pregnancy & Lactation
Pregnancy Category B. Use if clearly needed and benefits outweigh risks. Caution is advised during lactation; consult a doctor.
Side Effects
Contraindications
- Hypersensitivity to azithromycin or any other macrolide antibiotic
- History of cholestatic jaundice/hepatic dysfunction associated with prior azithromycin use
Drug Interactions
Digoxin
May increase serum digoxin levels.
Antacids
May decrease the absorption of azithromycin; administer 2-4 hours apart.
Warfarin
May increase the risk of bleeding.
Nelfinavir
May increase azithromycin concentrations.
Storage
Store dry powder below 30°C, protected from light. Store reconstituted suspension at room temperature or refrigerated (as directed) and discard after the specified period.
Overdose
Symptoms of overdose may include severe nausea, vomiting, diarrhea, and abdominal pain. Symptomatic and supportive treatment should be initiated.
Pregnancy & Lactation
Pregnancy Category B. Use if clearly needed and benefits outweigh risks. Caution is advised during lactation; consult a doctor.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
Shelf life for unopened powder is typically 2-3 years. Reconstituted suspension has a shelf life of 5-10 days at room temperature, as per manufacturer's instructions.
Availability
Pharmacies and Hospitals
Approval Status
Approved by FDA and DGDA
Patent Status
Generic available (patent expired)
WHO Essential Medicine
YesClinical Trials
The efficacy and safety of Azithromycin have been established through numerous clinical trials, leading to its widespread use for various indications.
Lab Monitoring
- Liver function tests (for prolonged use)
- Renal function tests (in patients with severe renal impairment)
Doctor Notes
- Emphasize the importance of completing the full course of treatment.
- Monitor patients with hepatic impairment closely.
- Be aware of symptoms of Clostridium difficile-associated diarrhea.
- Use with caution in patients with known QT prolongation risk factors.
Patient Guidelines
- Complete the full course of medication as prescribed, even if you feel better.
- Shake the bottle well before each use.
- Use the provided measuring device for accurate dosing.
- Do not share your medication with others.
Missed Dose Advice
If a dose is missed, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.
Driving Precautions
Generally, it does not affect the ability to drive, but some patients may experience dizziness or blurred vision. If these side effects occur, avoid driving or operating heavy machinery.
Lifestyle Advice
- Stay hydrated by drinking plenty of fluids.
- Ensure adequate rest to aid recovery.
- Practice good hygiene to prevent the spread of infection.
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Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.
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