Nixon
Generic Name
Synthetic Antibacterial Agent 500 mg Injection
Manufacturer
PharmaCorp Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| nixon 500 mg injection | ৳ 150.45 | N/A |
Description
Overview of the medicine
Nixon 500 mg Injection is a broad-spectrum synthetic antibacterial agent used to treat a wide range of bacterial infections. It is effective against both Gram-positive and Gram-negative bacteria.
Uses & Indications
Dosage
Adults
500 mg IV or IM every 8-12 hours, depending on the severity of infection.
Elderly
No specific dosage adjustment is usually required unless there is significant renal impairment. Monitor renal function.
Renal_impairment
Dosage should be adjusted based on creatinine clearance. Consult a physician for specific recommendations.
How to Take
Nixon 500 mg Injection can be administered either intravenously (IV) or intramuscularly (IM). For IV administration, it should be slowly infused over 30-60 minutes. For IM administration, it should be injected deep into a large muscle mass.
Mechanism of Action
Nixon works by inhibiting bacterial protein synthesis, leading to the disruption of bacterial growth and multiplication. This action is primarily bacteriostatic at lower concentrations and bactericidal at higher concentrations against susceptible organisms.
Pharmacokinetics
Onset
Onset of action typically within 30 minutes following IV administration.
Excretion
Excreted mainly via the kidneys, with a small portion excreted in bile/faeces.
Half life
Plasma half-life ranges from 2 to 4 hours.
Absorption
Rapid and complete absorption following intramuscular (IM) or intravenous (IV) administration.
Metabolism
Primarily metabolized in the liver to inactive metabolites.
Side Effects
Contraindications
- •Known hypersensitivity to Nixon or any component of the formulation.
- •Severe renal impairment without dose adjustment.
Drug Interactions
Warfarin
May enhance the anticoagulant effect of warfarin, requiring monitoring of INR.
Probenecid
May increase the plasma concentration and prolong the half-life of Nixon by reducing renal tubular secretion.
Aminoglycosides
Concurrent use may increase the risk of nephrotoxicity.
Storage
Store below 30°C. Protect from light and moisture. Do not freeze. Keep the reconstituted solution stable for up to 24 hours at room temperature or 72 hours under refrigeration.
Overdose
In case of overdose, symptomatic and supportive treatment should be initiated. Hemodialysis may be considered in severe cases to remove the drug from the bloodstream.
Pregnancy & Lactation
Nixon should be used during pregnancy only if clearly needed and the potential benefits outweigh the potential risks to the fetus. It is excreted in breast milk; therefore, caution should be exercised when administered to a nursing mother. Consult your doctor.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
24 months from the date of manufacture.
Availability
Pharmacies, Hospitals
Approval Status
Approved by national regulatory authorities
Patent Status
Patent expired, generic available
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