Optimox
Generic Name
Moxifloxacin
Manufacturer
Popular Pharmaceuticals Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| optimox 05 eye drop | ৳ 200.00 | N/A |
Description
Overview of the medicine
Optimox-05 Eye Drop contains Moxifloxacin, a broad-spectrum fluoroquinolone antibiotic, used to treat bacterial conjunctivitis and other ocular infections. It works by inhibiting bacterial DNA gyrase and topoisomerase IV, essential enzymes for bacterial DNA replication.
Uses & Indications
Dosage
Adults
Instill 1 drop in the affected eye(s) 3 times daily for 7 days.
Elderly
No dosage adjustment required.
Renal_impairment
No dosage adjustment required for topical ocular administration.
How to Take
For ophthalmic use only. Tilt head back, pull down the lower eyelid to form a pouch, instill the drop, and close the eye gently. Avoid touching the dropper tip to any surface.
Mechanism of Action
Moxifloxacin inhibits bacterial DNA gyrase (topoisomerase II) and topoisomerase IV, enzymes necessary for bacterial DNA replication, transcription, repair, and recombination. Inhibition of these enzymes leads to bactericidal activity.
Pharmacokinetics
Onset
Rapid onset of action in ocular tissues.
Excretion
Primarily renal and fecal excretion for systemically absorbed drug.
Half life
Systemic half-life is about 12 hours, but ocular tissue half-life is shorter.
Absorption
Minimal systemic absorption after topical ocular administration.
Metabolism
Limited hepatic metabolism systemically; primarily excreted unchanged.
Side Effects
Contraindications
- Hypersensitivity to moxifloxacin or other quinolones
- Viral or fungal eye infections (as monotherapy)
Drug Interactions
Other Ophthalmic Preparations
If using multiple ophthalmic drops, administer them at least 5-10 minutes apart.
Storage
Store at room temperature (below 30°C). Protect from light and moisture. Do not freeze.
Overdose
An ocular overdose is unlikely to cause systemic toxicity. If an overdose occurs, the eye can be flushed with lukewarm water.
Pregnancy & Lactation
Category C. Use only if potential benefit justifies the potential risk to the fetus. Caution should be exercised when administered to a nursing mother.
Side Effects
Contraindications
- Hypersensitivity to moxifloxacin or other quinolones
- Viral or fungal eye infections (as monotherapy)
Drug Interactions
Other Ophthalmic Preparations
If using multiple ophthalmic drops, administer them at least 5-10 minutes apart.
Storage
Store at room temperature (below 30°C). Protect from light and moisture. Do not freeze.
Overdose
An ocular overdose is unlikely to cause systemic toxicity. If an overdose occurs, the eye can be flushed with lukewarm water.
Pregnancy & Lactation
Category C. Use only if potential benefit justifies the potential risk to the fetus. Caution should be exercised when administered to a nursing mother.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
Typically 24 months (unopened). Discard 28 days after opening.
Availability
Pharmacies, Hospitals
Approval Status
Approved by major regulatory bodies (e.g., FDA, DGDA)
Patent Status
Generic available, original patent expired
WHO Essential Medicine
YesClinical Trials
Moxifloxacin ophthalmic solution has undergone extensive clinical trials demonstrating its efficacy and safety for bacterial conjunctivitis.
Lab Monitoring
- Not typically required for topical ophthalmic use.
Doctor Notes
- Emphasize the importance of completing the full course.
- Advise patients on proper administration technique to avoid contamination.
- Counsel on potential temporary blurred vision and contact lens precautions.
Patient Guidelines
- Complete the full course of treatment even if symptoms improve.
- Remove contact lenses before administration and wait at least 15 minutes before reinserting.
- Avoid sharing eye drops to prevent contamination.
Missed Dose Advice
If a dose is missed, apply it as soon as possible. If it is almost time for the next dose, skip the missed dose and resume the regular dosing schedule. Do not double the dose.
Driving Precautions
May cause temporary blurred vision. Advise patients to refrain from driving or operating machinery until vision is clear.
Lifestyle Advice
- Maintain good eye hygiene.
- Avoid rubbing eyes excessively.
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Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.
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