Sonexa
Generic Name
Moxifloxacin Hydrochloride Ophthalmic Solution
Manufacturer
Square Pharmaceuticals Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| sonexa 01 eye drop | ৳ 70.00 | N/A |
Description
Overview of the medicine
Sonexa-01 Eye Drop contains Moxifloxacin, a fluoroquinolone antibiotic used to treat bacterial conjunctivitis and other superficial bacterial ocular infections. It works by inhibiting bacterial DNA replication.
Uses & Indications
Dosage
Adults
1 drop in the affected eye(s) 3 times a day for 7 days.
Elderly
Same as adult dosage. No specific adjustment required.
Renal_impairment
No dosage adjustment required.
How to Take
For ophthalmic use only. Tilt head back, pull down lower eyelid to form a pouch, instill the drop, and close eye gently. Do not touch dropper tip to any surface.
Mechanism of Action
Moxifloxacin inhibits bacterial DNA gyrase and topoisomerase IV, enzymes essential for bacterial DNA replication, transcription, repair, and recombination. This leads to bacterial cell death.
Pharmacokinetics
Onset
Rapid, typically within hours for symptomatic relief.
Excretion
Primarily renal and fecal for systemically absorbed drug, but topical ocular absorption is minimal.
Half life
Systemic half-life is approximately 11-15 hours, but ocular tissue half-life is difficult to determine precisely and varies.
Absorption
Systemic absorption is minimal following topical ocular administration.
Metabolism
Primarily hepatic for systemically absorbed drug, but topical ocular absorption is minimal.
Side Effects
Contraindications
- Hypersensitivity to moxifloxacin or other quinolones
- Viral or fungal eye infections
Drug Interactions
No significant ophthalmic drug interactions
No significant ophthalmic drug interactions are typically reported for topical moxifloxacin due to minimal systemic absorption.
Storage
Store at controlled room temperature (20°C to 25°C). Do not freeze. Protect from light. Keep out of reach of children.
Overdose
Due to minimal systemic absorption, an ocular overdose is unlikely to cause systemic toxicity. Rinse eye with lukewarm water if excessive drops are administered.
Pregnancy & Lactation
Use during pregnancy and lactation only if clearly needed and the potential benefit outweighs the potential risk. Consult a doctor.
Side Effects
Contraindications
- Hypersensitivity to moxifloxacin or other quinolones
- Viral or fungal eye infections
Drug Interactions
No significant ophthalmic drug interactions
No significant ophthalmic drug interactions are typically reported for topical moxifloxacin due to minimal systemic absorption.
Storage
Store at controlled room temperature (20°C to 25°C). Do not freeze. Protect from light. Keep out of reach of children.
Overdose
Due to minimal systemic absorption, an ocular overdose is unlikely to cause systemic toxicity. Rinse eye with lukewarm water if excessive drops are administered.
Pregnancy & Lactation
Use during pregnancy and lactation only if clearly needed and the potential benefit outweighs the potential risk. Consult a doctor.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
24-36 months (unopened), 28 days (after opening).
Availability
Pharmacies, Hospitals
Approval Status
Approved by FDA
Patent Status
Off-patent
Clinical Trials
Multiple clinical trials have demonstrated the efficacy and safety of Moxifloxacin ophthalmic solution for bacterial conjunctivitis.
Lab Monitoring
- No specific lab monitoring required for topical ophthalmic use.
Doctor Notes
- Advise patients to avoid sharing eye drops.
- Emphasize proper administration technique to minimize contamination.
- Monitor for signs of secondary infection or worsening symptoms.
Patient Guidelines
- Complete the full course of treatment even if symptoms improve.
- Remove contact lenses before application and wait at least 15 minutes before reinserting.
- Avoid contaminating the dropper tip.
- Consult a doctor if symptoms worsen or persist.
Missed Dose Advice
If a dose is missed, apply it as soon as remembered. If it is almost time for the next dose, skip the missed dose and resume the regular schedule. Do not double the dose.
Driving Precautions
May cause temporary blurred vision. Avoid driving or operating machinery until vision is clear.
Lifestyle Advice
- Avoid rubbing eyes during infection.
- Maintain good hand hygiene.
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Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.
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