Sultolin
Generic Name
Salbutamol (Albuterol)
Manufacturer
Square Pharmaceuticals Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| sultolin 2 mg syrup | ৳ 23.00 | N/A |
Description
Overview of the medicine
Sultolin 2 mg syrup is a bronchodilator used for the relief of bronchospasm in conditions such as asthma and chronic obstructive pulmonary disease (COPD). It helps to open airways in the lungs, making breathing easier.
Uses & Indications
Dosage
Adults
Adults: 2 mg to 4 mg (5 ml to 10 ml) three or four times daily.
Elderly
Elderly: Initially 2 mg (5 ml) three or four times daily. May be increased if necessary.
Renal_impairment
Renal impairment: No dose adjustment usually necessary, but monitor for adverse effects.
How to Take
Administer orally. May be taken with or without food. Use a measuring spoon or cup to ensure accurate dosing.
Mechanism of Action
Salbutamol is a selective short-acting beta-2 adrenoceptor agonist. It works by stimulating beta-2 receptors in the smooth muscles of the bronchial tree, leading to relaxation of these muscles and bronchodilation.
Pharmacokinetics
Onset
Onset of bronchodilation typically within 30 minutes after oral administration.
Excretion
Excreted mainly in the urine, both as unchanged drug and metabolites.
Half life
Plasma half-life is approximately 4-6 hours.
Absorption
Rapidly absorbed from the gastrointestinal tract. Peak plasma concentrations are reached within 2-3 hours after oral administration.
Metabolism
Undergoes extensive metabolism in the liver to an inactive sulfate conjugate.
Side Effects
Contraindications
- Hypersensitivity to salbutamol or any component of the formulation
- Thyrotoxicosis (relative contraindication)
Drug Interactions
Diuretics (e.g., Furosemide)
May potentiate hypokalemia associated with high doses of salbutamol.
Beta-blockers (e.g., Propranolol)
May antagonize the bronchodilatory effects of salbutamol.
MAOIs and TCAs (e.g., Phenelzine, Amitriptyline)
Increased risk of cardiovascular effects.
Storage
Store below 30°C. Protect from light and moisture. Do not freeze. Keep out of reach of children.
Overdose
Symptoms include tachycardia, tremors, headache, and hypokalemia. Treatment involves symptomatic and supportive measures. Cardiology monitoring may be required in severe cases.
Pregnancy & Lactation
Pregnancy Category C. Use only if the potential benefit justifies the potential risk to the fetus. Salbutamol is excreted in breast milk; caution should be exercised when administered to a nursing mother.
Side Effects
Contraindications
- Hypersensitivity to salbutamol or any component of the formulation
- Thyrotoxicosis (relative contraindication)
Drug Interactions
Diuretics (e.g., Furosemide)
May potentiate hypokalemia associated with high doses of salbutamol.
Beta-blockers (e.g., Propranolol)
May antagonize the bronchodilatory effects of salbutamol.
MAOIs and TCAs (e.g., Phenelzine, Amitriptyline)
Increased risk of cardiovascular effects.
Storage
Store below 30°C. Protect from light and moisture. Do not freeze. Keep out of reach of children.
Overdose
Symptoms include tachycardia, tremors, headache, and hypokalemia. Treatment involves symptomatic and supportive measures. Cardiology monitoring may be required in severe cases.
Pregnancy & Lactation
Pregnancy Category C. Use only if the potential benefit justifies the potential risk to the fetus. Salbutamol is excreted in breast milk; caution should be exercised when administered to a nursing mother.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
Typically 24-36 months from manufacturing date when stored correctly.
Availability
Available in pharmacies, hospitals, and clinics worldwide
Approval Status
Approved by regulatory bodies worldwide (e.g., FDA, DGDA)
Patent Status
Generic available, patent expired
WHO Essential Medicine
YesClinical Trials
Salbutamol has been extensively studied in numerous clinical trials demonstrating its efficacy and safety for respiratory conditions.
Lab Monitoring
- Monitor serum potassium levels, especially in patients receiving high doses or concomitant diuretics.
- Monitor blood glucose in diabetic patients.
Doctor Notes
- Emphasize proper use and adherence to prescribed dosage.
- Advise patients to seek medical advice if their symptoms worsen despite regular use.
- Consider alternative treatments or combination therapy if patients require frequent use of a short-acting beta-agonist.
Patient Guidelines
- Do not exceed the recommended dose.
- Inform your doctor about all other medications you are taking.
- Seek immediate medical attention if breathing difficulties worsen or do not improve.
Missed Dose Advice
If a dose is missed, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and resume your regular dosing schedule. Do not double the dose to catch up.
Driving Precautions
Salbutamol may cause tremor or dizziness in some patients. Patients should be advised to exercise caution when driving or operating machinery until they know how the medication affects them.
Lifestyle Advice
- Avoid smoking as it worsens respiratory conditions.
- Maintain a healthy lifestyle with regular exercise and a balanced diet.
- Identify and avoid triggers for asthma or COPD exacerbations.
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Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.
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