Sultolin
Generic Name
Salbutamol
Manufacturer
XYZ Pharma Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| sultolin 200 mcg inhalation capsule | ৳ 2.51 | ৳ 15.06 |
Description
Overview of the medicine
Sultolin 200 mcg Inhalation Capsule contains Salbutamol, a fast-acting bronchodilator used to relieve symptoms of asthma and COPD.
Uses & Indications
Dosage
Adults
200-400 mcg (1-2 capsules) via inhaler 3-4 times daily as needed. For prevention of exercise-induced bronchospasm: 200 mcg 10-15 minutes before exercise.
Elderly
Similar to adult dose, but may require lower initial doses. Monitor closely.
Renal_impairment
No specific dose adjustment generally needed, but monitor closely for side effects.
How to Take
For oral inhalation only. The capsule should be placed into a suitable dry powder inhaler device (e.g., Rotahaler) and the contents inhaled as directed by the physician. Do not swallow the capsule.
Mechanism of Action
Salbutamol selectively stimulates beta-2 adrenergic receptors in bronchial smooth muscle, causing relaxation and bronchodilation. It also inhibits the release of mast cell mediators.
Pharmacokinetics
Onset
5-15 minutes
Excretion
Excreted mainly in the urine, both as unchanged drug and its metabolite.
Half life
4-6 hours (systemic)
Absorption
Rapidly absorbed after inhalation. Systemic bioavailability is low due to first-pass metabolism.
Metabolism
Primarily metabolized in the liver to an inactive sulfate conjugate.
Side Effects
Contraindications
- •Hypersensitivity to salbutamol or any component of the formulation
- •Tachyarrhythmia
Drug Interactions
Diuretics
May cause ECG changes and/or hypokalemia, especially with high doses.
Beta-blockers
Can cause severe bronchospasm in asthmatics and inhibit the bronchodilatory effect of salbutamol.
Tricyclic Antidepressants (TCAs) & MAOIs
May potentiate the cardiovascular effects of salbutamol.
Storage
Store below 30°C in a dry place, protected from direct sunlight and moisture. Keep out of reach of children.
Overdose
Symptoms include tachycardia, tremors, palpitations, headache, and hypokalemia. Management involves symptomatic and supportive care, monitoring electrolyte levels.
Pregnancy & Lactation
Pregnancy Category C. Use only if the potential benefit justifies the potential risk to the fetus. Small amounts may be excreted in breast milk; use with caution.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
Typically 2-3 years from manufacturing date. Refer to the packaging for the exact expiry date.
Availability
Pharmacies nationwide
Approval Status
Approved
Patent Status
Off-patent
WHO Essential Medicine
YesAlternative Medicines in Bangladesh
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Global Brand Names
International brand names for this medicine
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