Trialon
Generic Name
Triamcinolone Acetonide 0.01% Cream
Manufacturer
Reputable Pharma Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| trialon 01 cream | ৳ 25.00 | N/A |
Description
Overview of the medicine
Trialon-01 Cream contains Triamcinolone Acetonide, a synthetic corticosteroid used topically for various inflammatory skin conditions such as eczema, psoriasis, and dermatitis.
Uses & Indications
Dosage
Adults
Apply a thin layer to the affected skin area 2-3 times daily, or as directed by a physician.
Elderly
No specific dosage adjustments required; use with caution due to potential for thinner skin and increased absorption.
Renal_impairment
Topical application does not usually require dosage adjustment for renal impairment due to minimal systemic absorption.
How to Take
For external use only. Wash hands before and after application. Apply a thin film to the affected skin area and rub in gently. Do not apply to open wounds, mucous membranes, or near eyes. Avoid prolonged use, especially on the face or in skin folds.
Mechanism of Action
Triamcinolone Acetonide acts as an anti-inflammatory and antipruritic agent by inducing phospholipase A2 inhibitory proteins, lipocortins, which control the biosynthesis of potent mediators of inflammation such as prostaglandins and leukotrienes.
Pharmacokinetics
Onset
Topical effect usually observed within hours to days.
Excretion
Excreted mainly by the kidneys; small amounts via bile.
Half life
Not specifically determined for topical application; systemic half-life of oral triamcinolone is 2-5 hours.
Absorption
Minimal systemic absorption through intact skin; absorption increases with skin damage, occlusion, or application to large areas.
Metabolism
Primarily metabolized in the liver to inactive metabolites.
Side Effects
Contraindications
- Hypersensitivity to Triamcinolone Acetonide or any component of the cream.
- Untreated fungal, viral, or bacterial infections of the skin.
- Rosacea, perioral dermatitis, acne vulgaris.
- Pruritus without inflammation.
Drug Interactions
None known
No significant systemic drug interactions are expected due to minimal systemic absorption with proper topical use.
Storage
Store below 30°C in a dry place, protected from light and moisture. Do not freeze. Keep out of reach of children.
Overdose
Acute overdose is unlikely with topical application. Chronic overdose or misuse (e.g., prolonged use, application to large areas or under occlusion) may lead to systemic corticosteroid effects like Cushing's syndrome or adrenal suppression. Discontinue gradually under medical supervision.
Pregnancy & Lactation
Use during pregnancy only if the potential benefit justifies the potential risk to the fetus. Avoid extensive use or prolonged treatment. Exercise caution when administered to a nursing mother; it is unknown whether topical corticosteroids are excreted in human milk.
Side Effects
Contraindications
- Hypersensitivity to Triamcinolone Acetonide or any component of the cream.
- Untreated fungal, viral, or bacterial infections of the skin.
- Rosacea, perioral dermatitis, acne vulgaris.
- Pruritus without inflammation.
Drug Interactions
None known
No significant systemic drug interactions are expected due to minimal systemic absorption with proper topical use.
Storage
Store below 30°C in a dry place, protected from light and moisture. Do not freeze. Keep out of reach of children.
Overdose
Acute overdose is unlikely with topical application. Chronic overdose or misuse (e.g., prolonged use, application to large areas or under occlusion) may lead to systemic corticosteroid effects like Cushing's syndrome or adrenal suppression. Discontinue gradually under medical supervision.
Pregnancy & Lactation
Use during pregnancy only if the potential benefit justifies the potential risk to the fetus. Avoid extensive use or prolonged treatment. Exercise caution when administered to a nursing mother; it is unknown whether topical corticosteroids are excreted in human milk.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
24 months from manufacturing date.
Availability
Pharmacies and Hospitals
Approval Status
Approved by DGDA
Patent Status
Off-patent
Clinical Trials
Triamcinolone Acetonide has been extensively studied in numerous clinical trials demonstrating its efficacy and safety for various inflammatory dermatoses when applied topically.
Lab Monitoring
- Not generally required for short-term, localized topical use.
- Adrenal function tests (e.g., plasma cortisol levels) if prolonged or extensive use is anticipated, particularly in pediatric patients.
Doctor Notes
- Educate patients on the appropriate use of topical corticosteroids, emphasizing the shortest effective duration and avoiding sensitive areas.
- Monitor patients, especially children, for signs of systemic absorption (e.g., growth retardation, Cushingoid features) during prolonged treatment.
- Advise against self-medication for prolonged periods or for conditions not explicitly diagnosed.
Patient Guidelines
- Use only as directed by a healthcare professional.
- Do not cover the treated area with bandages or other occlusive dressings unless advised by a doctor.
- Report any worsening of symptoms or signs of infection (e.g., pus, fever) to your doctor.
- Avoid using on the face, groin, or axillae unless specifically instructed by a doctor.
- Wash hands thoroughly after application.
Missed Dose Advice
If you miss a dose, apply it as soon as you remember. If it is almost time for your next dose, skip the missed dose and resume your regular dosing schedule. Do not apply extra cream to make up for a missed dose.
Driving Precautions
Trialon-01 Cream is for topical use and is unlikely to affect the ability to drive or operate machinery.
Lifestyle Advice
- Keep the treated skin clean and dry.
- Avoid irritants that may worsen your skin condition, such as harsh soaps, detergents, or certain fabrics.
- Wear loose-fitting clothing over treated areas.
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