Trialon
Generic Name
Trialon-01 Oral Paste
Manufacturer
MediCorp Pharmaceuticals
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| trialon 01 oral paste | ৳ 100.30 | N/A |
Description
Overview of the medicine
Trialon-01 Oral Paste is an anti-inflammatory and immunosuppressive medication used for topical application in the oral cavity. It helps reduce inflammation, pain, and discomfort associated with various oral lesions.
Uses & Indications
Dosage
Adults
Apply a thin film of the paste to the affected area with a clean finger or cotton swab, 2-3 times daily, preferably after meals and at bedtime. Do not rub in. Discontinue use once symptoms resolve or after 5-7 days.
Elderly
No special dosage adjustments are typically required for elderly patients, but caution should be exercised due to potential increased sensitivity.
Renal_impairment
No dosage adjustment necessary as systemic absorption is minimal.
How to Take
Apply a small amount of paste directly to the oral lesion, pressing gently to form a thin film. Do not rub in. For best results, apply after meals and at bedtime to allow maximum contact time.
Mechanism of Action
Trialon-01 (a corticosteroid) exerts its action by inducing phospholipase A2 inhibitory proteins, thereby controlling the biosynthesis of potent mediators of inflammation such as prostaglandins and leukotrienes. It also possesses immunosuppressive properties.
Pharmacokinetics
Onset
Local symptomatic relief typically begins within a few hours of application.
Excretion
Metabolites are excreted mainly via the kidneys.
Half life
Not well-characterized for topical oral application due to minimal systemic absorption.
Absorption
Systemic absorption from oral paste is generally minimal, particularly when applied to the oral mucosa. However, significant absorption can occur with extensive use, prolonged application, or use under occlusive conditions.
Metabolism
Any absorbed portion is metabolized primarily in the liver.
Side Effects
Contraindications
- Hypersensitivity to Trialon-01 or any components of the paste.
- Oral fungal, viral (e.g., herpes simplex), or bacterial infections.
- Tuberculosis of the oral cavity.
- Perioral dermatitis or rosacea affecting the oral area.
Drug Interactions
No significant systemic drug interactions are expected
Due to minimal systemic absorption, clinically significant drug interactions are unlikely with typical use of Trialon-01 Oral Paste.
Storage
Store below 30°C. Protect from light and moisture. Keep out of reach of children. Do not freeze.
Overdose
Overdose is highly unlikely with topical oral application. If a large amount is accidentally ingested, supportive care may be given. Long-term excessive use could lead to systemic corticosteroid effects, though rare.
Pregnancy & Lactation
Use with caution during pregnancy and lactation. Consult a doctor before use. Minimal systemic absorption suggests low risk, but safety has not been established.
Side Effects
Contraindications
- Hypersensitivity to Trialon-01 or any components of the paste.
- Oral fungal, viral (e.g., herpes simplex), or bacterial infections.
- Tuberculosis of the oral cavity.
- Perioral dermatitis or rosacea affecting the oral area.
Drug Interactions
No significant systemic drug interactions are expected
Due to minimal systemic absorption, clinically significant drug interactions are unlikely with typical use of Trialon-01 Oral Paste.
Storage
Store below 30°C. Protect from light and moisture. Keep out of reach of children. Do not freeze.
Overdose
Overdose is highly unlikely with topical oral application. If a large amount is accidentally ingested, supportive care may be given. Long-term excessive use could lead to systemic corticosteroid effects, though rare.
Pregnancy & Lactation
Use with caution during pregnancy and lactation. Consult a doctor before use. Minimal systemic absorption suggests low risk, but safety has not been established.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
24 months from the date of manufacture when stored properly.
Availability
Available in pharmacies
Approval Status
Approved (Hypothetical)
Patent Status
Off-patent
Clinical Trials
Information regarding specific clinical trials for Trialon-01 Oral Paste is available upon request from the manufacturer.
Lab Monitoring
- Not routinely required due to minimal systemic absorption.
Doctor Notes
- Advise patients on correct application technique and to avoid rubbing the paste.
- Emphasize limiting use duration to 5-7 days unless persistent lesions require longer therapy under close supervision.
- Be vigilant for signs of oral candidiasis, especially with prolonged use, and treat appropriately.
Patient Guidelines
- Apply only to the affected area as directed by your doctor.
- Do not swallow the paste. Rinse mouth thoroughly if accidentally ingested.
- Maintain good oral hygiene.
- Avoid eating or drinking for at least 30 minutes after application to ensure maximum contact time.
- Do not use for more than 5-7 days unless specifically advised by a doctor.
Missed Dose Advice
If you miss a dose, apply it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not apply a double dose.
Driving Precautions
Trialon-01 Oral Paste is not expected to affect the ability to drive or operate machinery.
Lifestyle Advice
- Avoid irritating foods (spicy, acidic) that may worsen oral lesions.
- Maintain proper dental hygiene to prevent secondary infections.
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Global Brand Names
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