Cipro-A
Generic Name
Ciprofloxacin 0.3% ophthalmic solution
Manufacturer
XYZ Pharmaceuticals Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| cipro a 03 eye drop | ৳ 50.00 | N/A |
Description
Overview of the medicine
Ciprofloxacin 0.3% eye drop is an ophthalmic antibiotic used to treat bacterial infections of the eye, such as conjunctivitis and corneal ulcers.
Uses & Indications
Dosage
Adults
Bacterial Conjunctivitis: 1-2 drops into the affected eye(s) 4 times daily for 5-7 days. For severe infections, 1-2 drops every 2 hours while awake for 2 days, then 1-2 drops every 4 hours while awake for 5 days. Corneal Ulcers: 2 drops into the affected eye(s) every 15 minutes for the first 6 hours, then 2 drops every 30 minutes for the remainder of the first day. On day 2, 2 drops every hour. On days 3-14, 2 drops every 4 hours. Treatment may continue beyond 14 days if needed.
Elderly
No dosage adjustment necessary.
Renal_impairment
No dosage adjustment necessary for ophthalmic use.
How to Take
For ophthalmic use only. Tilt head back, pull down the lower eyelid to form a pouch, instill the prescribed number of drops, and close the eye gently. Do not touch the dropper tip to any surface.
Mechanism of Action
Ciprofloxacin acts by inhibiting bacterial DNA gyrase and topoisomerase IV, enzymes essential for bacterial DNA replication, transcription, repair, and recombination, leading to cell death.
Pharmacokinetics
Onset
Rapid onset of antibacterial action within the eye.
Excretion
Minimal systemic excretion of unchanged drug. Locally, it is cleared by tear turnover.
Half life
Not clinically significant systemically due to minimal absorption. Ocular tissue concentrations are maintained for several hours.
Absorption
Minimal systemic absorption after ocular administration. Primarily acts locally.
Metabolism
Minimal ocular metabolism.
Side Effects
Contraindications
- Hypersensitivity to ciprofloxacin or other quinolone antibiotics.
- Hypersensitivity to any component of the formulation.
Drug Interactions
Other topical ophthalmic medications
If more than one topical ophthalmic medication is being used, they should be administered at least 5-10 minutes apart.
Storage
Store at room temperature (below 30°C). Protect from light. Do not freeze. Keep out of reach of children.
Overdose
An ophthalmic overdose is unlikely to cause systemic toxicity due to minimal absorption. Flush the eye with lukewarm water if an overdose occurs.
Pregnancy & Lactation
Pregnancy Category C. Use only if the potential benefit justifies the potential risk to the fetus. It is unknown whether ciprofloxacin is excreted in human milk after ophthalmic use; however, due to minimal systemic absorption, adverse effects on breastfed infants are unlikely.
Side Effects
Contraindications
- Hypersensitivity to ciprofloxacin or other quinolone antibiotics.
- Hypersensitivity to any component of the formulation.
Drug Interactions
Other topical ophthalmic medications
If more than one topical ophthalmic medication is being used, they should be administered at least 5-10 minutes apart.
Storage
Store at room temperature (below 30°C). Protect from light. Do not freeze. Keep out of reach of children.
Overdose
An ophthalmic overdose is unlikely to cause systemic toxicity due to minimal absorption. Flush the eye with lukewarm water if an overdose occurs.
Pregnancy & Lactation
Pregnancy Category C. Use only if the potential benefit justifies the potential risk to the fetus. It is unknown whether ciprofloxacin is excreted in human milk after ophthalmic use; however, due to minimal systemic absorption, adverse effects on breastfed infants are unlikely.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
Typically 24-36 months. Discard 28 days after opening the bottle.
Availability
Pharmacies, Hospitals
Approval Status
Approved
Patent Status
Off-patent (Generic available)
WHO Essential Medicine
YesClinical Trials
Extensively studied and proven effective in clinical trials for treating various bacterial ocular infections.
Lab Monitoring
- Not typically required for ophthalmic ciprofloxacin due to minimal systemic absorption.
Doctor Notes
- Emphasize the importance of completing the full course of therapy, even if symptoms improve.
- Advise patients about proper administration technique to avoid contamination and maximize efficacy.
- Caution against sharing eye drops to prevent cross-contamination.
Patient Guidelines
- Wash hands thoroughly before and after applying the eye drops.
- Do not touch the dropper tip to your eye or any other surface to avoid contamination.
- Remove contact lenses before applying the drops and wait at least 15 minutes before reinserting them.
- Complete the full course of treatment, even if symptoms improve, to prevent recurrence and resistance.
Missed Dose Advice
If a dose is missed, apply it as soon as possible. If it is almost time for the next dose, skip the missed dose and resume your regular dosing schedule. Do not double the dose.
Driving Precautions
May cause temporary blurred vision or discomfort after administration. Patients should avoid driving or operating machinery until vision is clear.
Lifestyle Advice
- Avoid wearing contact lenses during the course of treatment for bacterial eye infections.
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