Ciprozid
Generic Name
Ciprofloxacin 0.3% Ophthalmic Solution
Manufacturer
Square Pharmaceuticals Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| ciprozid 03 eye drop | ৳ 50.00 | N/A |
Description
Overview of the medicine
Ciprozid 0.3% Eye Drop is an antibiotic medication used to treat bacterial eye infections. It belongs to a group of drugs called fluoroquinolones, which work by stopping the growth of bacteria. It is effective against a wide range of bacteria.
Uses & Indications
Dosage
Adults
Bacterial Conjunctivitis: 1-2 drops into the conjunctival sac of the affected eye(s) every 2 hours while awake for 2 days, then 1-2 drops every 4 hours while awake for the next 5 days. Corneal Ulcers: 2 drops into the affected eye every 15 minutes for the first 6 hours, then 2 drops every 30 minutes for the remainder of the first day. On the second day, 2 drops hourly. On days 3-14, 2 drops every 4 hours. Treatment may continue beyond 14 days if epithelization has not occurred.
Elderly
No specific dosage adjustment is necessary for elderly patients.
Renal_impairment
No dosage adjustment is necessary for ophthalmic use due to minimal systemic absorption.
How to Take
For ophthalmic use only. Tilt head back, pull down lower eyelid to create a pouch. Instill the prescribed number of drops into the pouch. Close eye gently for 1-2 minutes. Do not touch the dropper tip to any surface to avoid contamination. If using other eye medications, wait at least 5 minutes between applications.
Mechanism of Action
Ciprofloxacin inhibits bacterial DNA gyrase and topoisomerase IV, enzymes essential for bacterial DNA replication, transcription, repair, and recombination. This leads to disruption of bacterial DNA and cell death.
Pharmacokinetics
Onset
Within hours of administration, clinical improvement often seen within 2-3 days.
Excretion
Mainly through kidneys (systemically); locally, cleared with tears and blinking.
Half life
Not relevant for ophthalmic use due to minimal systemic absorption; systemic half-life is 3-5 hours.
Absorption
Systemic absorption from ophthalmic administration is minimal. Most of the drug remains localized in the ocular tissues.
Metabolism
Minimal metabolism in ocular tissues; systemically, primarily hepatic.
Side Effects
Contraindications
- Hypersensitivity to ciprofloxacin, other quinolones, or any component of the formulation
Drug Interactions
Other topical ophthalmic medications
If more than one topical ophthalmic drug is being used, they should be administered at least 5 minutes apart.
Storage
Store at controlled room temperature (20°C to 25°C). Protect from light. Do not freeze.
Overdose
An overdose of ophthalmic ciprofloxacin is unlikely to cause systemic toxicity due to minimal systemic absorption. If accidentally ingested, symptomatic treatment may be required. Local irritation may occur with excessive topical application.
Pregnancy & Lactation
Pregnancy Category C. Use only if potential benefit outweighs potential risk to the fetus. Ciprofloxacin is excreted in human milk after systemic administration, but systemic absorption from ophthalmic administration is minimal. Use with caution in nursing mothers.
Side Effects
Contraindications
- Hypersensitivity to ciprofloxacin, other quinolones, or any component of the formulation
Drug Interactions
Other topical ophthalmic medications
If more than one topical ophthalmic drug is being used, they should be administered at least 5 minutes apart.
Storage
Store at controlled room temperature (20°C to 25°C). Protect from light. Do not freeze.
Overdose
An overdose of ophthalmic ciprofloxacin is unlikely to cause systemic toxicity due to minimal systemic absorption. If accidentally ingested, symptomatic treatment may be required. Local irritation may occur with excessive topical application.
Pregnancy & Lactation
Pregnancy Category C. Use only if potential benefit outweighs potential risk to the fetus. Ciprofloxacin is excreted in human milk after systemic administration, but systemic absorption from ophthalmic administration is minimal. Use with caution in nursing mothers.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
Typically 2-3 years unopened. Discard 28 days after opening.
Availability
Pharmacies, Hospitals
Approval Status
Approved
Patent Status
Generic available
WHO Essential Medicine
YesClinical Trials
Extensively studied and clinically proven for the treatment of bacterial conjunctivitis and corneal ulcers.
Lab Monitoring
- Not typically required for ophthalmic ciprofloxacin.
Doctor Notes
- Advise patients on proper instillation technique to minimize contamination.
- Monitor for signs of superinfection or lack of clinical improvement.
Patient Guidelines
- Do not wear contact lenses during treatment for bacterial eye infections.
- Wash hands thoroughly before and after applying the eye drops.
- Do not share eye drops with others.
Missed Dose Advice
If you miss a dose, apply it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not apply a double dose to make up for a missed one.
Driving Precautions
May cause temporary blurred vision. Avoid driving or operating machinery until vision is clear.
Lifestyle Advice
- Avoid rubbing the eyes.
- Maintain good ocular hygiene.
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Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.
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