D3

Oral administration. Tablets can be taken with or without food, but absorption is better with a fatty meal.

Cholecalciferol is biologically inactive but is hydroxylated in the liver to 25-hydroxycholecalciferol (calcifediol) and then in the kidneys to 1,25-dihydroxycholecalciferol (calcitriol). Calcitriol is the active form that promotes calcium and phosphate absorption from the intestine, regulates bone metabolism, and supports immune function.

• Hypercalcemia
• Hypervitaminosis D
• Malabsorption syndrome (severe)
• Severe renal osteodystrophy with hyperphosphatemia

Store below 30°C in a cool, dry place. Protect from light and moisture. Keep out of reach of children.

Symptoms of overdose include hypercalcemia, hypercalciuria, nausea, vomiting, polyuria, thirst, and weakness. Severe cases can lead to renal impairment. Management involves discontinuing vitamin D, restricting dietary calcium, increasing fluid intake, and in severe cases, corticosteroids.

Generally considered safe at physiological doses during pregnancy and lactation. High doses should be avoided as they may be harmful. Consult a healthcare provider before use.

• Hypercalcemia
• Hypervitaminosis D
• Malabsorption syndrome (severe)
• Severe renal osteodystrophy with hyperphosphatemia

Store below 30°C in a cool, dry place. Protect from light and moisture. Keep out of reach of children.

Symptoms of overdose include hypercalcemia, hypercalciuria, nausea, vomiting, polyuria, thirst, and weakness. Severe cases can lead to renal impairment. Management involves discontinuing vitamin D, restricting dietary calcium, increasing fluid intake, and in severe cases, corticosteroids.

Generally considered safe at physiological doses during pregnancy and lactation. High doses should be avoided as they may be harmful. Consult a healthcare provider before use.