Lifcin
Generic Name
Ciprofloxacin Ophthalmic Solution
Manufacturer
Acme Pharmaceuticals Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| lifcin 15 eye drop | ৳ 130.00 | N/A |
Description
Overview of the medicine
Lifcin-15 Eye Drop is an antibiotic ophthalmic solution containing Ciprofloxacin, a broad-spectrum fluoroquinolone. It is used to treat various bacterial infections of the eye.
Uses & Indications
Dosage
Adults
For bacterial conjunctivitis: 1-2 drops into the affected eye(s) every 4 hours for 5-7 days. For severe infections like corneal ulcers: 2 drops into the affected eye(s) every 15 minutes for the first 6 hours, then 2 drops every 30 minutes for the remainder of the first day, then 2 drops every hour on day 2, and then 2 drops every 4 hours for the subsequent days, or as directed by physician.
Elderly
No specific dosage adjustment required for elderly patients.
Renal_impairment
Not applicable for topical ophthalmic use due to minimal systemic absorption.
How to Take
For ophthalmic use only. Tilt head back, pull down the lower eyelid to create a pouch, and instill the prescribed number of drops. Close eye gently for 1-2 minutes. Avoid touching the dropper tip to any surface.
Mechanism of Action
Ciprofloxacin, a fluoroquinolone, inhibits bacterial DNA gyrase and topoisomerase IV, enzymes essential for bacterial DNA replication, transcription, repair, and recombination. This leads to disruption of bacterial DNA and cell death.
Pharmacokinetics
Onset
Within minutes to hours for symptomatic relief and bacterial load reduction.
Excretion
Primarily renal excretion for the small amount systemically absorbed.
Half life
Ocular half-life not precisely defined due to minimal systemic absorption; systemic half-life is approximately 3-5 hours.
Absorption
Minimal systemic absorption occurs after topical ophthalmic administration. Peak concentrations are achieved in the ocular tissues.
Metabolism
Minimal systemic metabolism; primary metabolism is hepatic.
Side Effects
Contraindications
- Hypersensitivity to ciprofloxacin or other quinolones, or to any component of the formulation.
- Viral or fungal infections of the eye (unless co-existing bacterial infection is treated).
Drug Interactions
None significant for ophthalmic use.
Systemic drug interactions are unlikely due to minimal systemic absorption. However, if multiple ophthalmic medications are used, administer them at least 5 minutes apart.
Storage
Store at room temperature (below 30°C). Protect from light and moisture. Do not freeze.
Overdose
An acute overdose is unlikely with ophthalmic application. If swallowed, supportive measures should be taken.
Pregnancy & Lactation
Use in pregnancy only if the potential benefit outweighs the potential risk to the fetus. Ciprofloxacin is excreted in human milk; caution should be exercised when administered to a nursing mother. Consult a doctor.
Side Effects
Contraindications
- Hypersensitivity to ciprofloxacin or other quinolones, or to any component of the formulation.
- Viral or fungal infections of the eye (unless co-existing bacterial infection is treated).
Drug Interactions
None significant for ophthalmic use.
Systemic drug interactions are unlikely due to minimal systemic absorption. However, if multiple ophthalmic medications are used, administer them at least 5 minutes apart.
Storage
Store at room temperature (below 30°C). Protect from light and moisture. Do not freeze.
Overdose
An acute overdose is unlikely with ophthalmic application. If swallowed, supportive measures should be taken.
Pregnancy & Lactation
Use in pregnancy only if the potential benefit outweighs the potential risk to the fetus. Ciprofloxacin is excreted in human milk; caution should be exercised when administered to a nursing mother. Consult a doctor.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
24 months (unopened). Discard 28 days after opening.
Availability
Available in pharmacies and hospitals nationwide
Approval Status
Approved by DGDA (Bangladesh)
Patent Status
Generic available, off-patent
Clinical Trials
Ciprofloxacin ophthalmic solutions have been extensively studied in numerous clinical trials demonstrating efficacy and safety for bacterial conjunctivitis and keratitis.
Lab Monitoring
- Not typically required for topical ophthalmic use.
Doctor Notes
- Emphasize proper administration technique to patients.
- Monitor for signs of superinfection or allergic reactions.
- Advise patients on contact lens use during treatment.
Patient Guidelines
- Wash hands thoroughly before and after applying the eye drops.
- Avoid touching the dropper tip to the eye or any other surface to prevent contamination.
- Remove contact lenses before application and wait at least 15 minutes before reinserting.
- Do not share your eye drops with anyone else.
Missed Dose Advice
If a dose is missed, apply it as soon as possible. If it is almost time for the next dose, skip the missed dose and resume the regular dosing schedule. Do not double the dose.
Driving Precautions
May cause temporary blurring of vision. If vision is blurred, avoid driving or operating machinery until vision clears.
Lifestyle Advice
- Avoid rubbing your eyes.
- Maintain good ocular hygiene.
- Follow the full course of treatment even if symptoms improve.
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International brand names for this medicine. Click a brand to search for detailed information.
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